Results 141 to 150 of about 17,303 (261)

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Activatable smart contrast agents for photoacoustic imaging

Smart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh, Jihye Lee, Suyoung Park, Juyoung Yoon, Won Jong Kim, Chulhong Kim   +5 more
wiley   +1 more source

بررسی اثر فتوتوکسيک عصارۀ گياه هوفاريقون بر Enterococcus Faecalis، Staphylococcus Aureus و Escherichia Coli [PDF]

, 2013
مقدمه: عصارۀ گياه هوفاريقون با نام علمی Hypericum Perforatum L. به‌عنوان يک حساس‌گر نوری جديد برای درمان فتوديناميکی در چندين مطالعۀ آزمايشگاهی مورد بررسی قرار گرفته است.
اسماعيلی‌جاويد, غلامرضا, برقعی, ياسمن‌سادات, کاشف, نسيم   +2 more
core  

Bimetallic Nanozymes/Polypyrrole/Methylene Blue Platform for Photothermal and Catalytic Biofilm Disruption and Angiogenesis Enhancement in Diabetic Wound Healing

Small Science, EarlyView.
The bimetallic ceria‐zinc nanoflowers coated with polypyrrole and loaded with methylene blue disrupt methicillin‐resistant Staphylococcus aureus biofilms synergistically, promote angiogenesis, thereby achieving efficient diabetic wound healing. Integrated photothermal therapy optimized, photodynamic therapy enhanced, pH‐mediated multifunctional ...
Prafful P. Kothari, Tonmoy Banerjee, Balaram Ghosh, Swati Biswas   +3 more
wiley   +1 more source

Preparation of Aqueous Solutions with Information on Solids Using Natural Polymers by Solid‐State Mixing

The Chemical Record, EarlyView.
The solid‐state information, such as chiral crystal formation, crystal polymorphism, mechanochromism, room‐temperature phosphorescence, and fluorescence detection by molecular recognition, is maintained even when the functional guest molecules are solubilized in water using natural polymers.
Keita Yamana, Riku Kawasaki, Atsushi Ikeda   +2 more
wiley   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

KOH 5% solution versus diclofenac 3% for the treatment of actinic keratosis – Results from a three‐armed RCT

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In this RCT, KOH 5% demonstrated superior clinical success to diclofenac 3% and placebo at the end of treatment in patients with mild‐to‐moderate actinic keratosis and comparable long‐term efficacy to diclofenac. Its fast onset of efficacy and favourable tolerability make KOH a valuable treatment option in early‐stage actinic keratosis treatment ...
U. Reinhold, N. Leitz, R. Dominicus, E. L. Szabó, T. Dirschka, G. Popp, T. C. Fischer, N. Adamini, R. Ostendorf, M. Asefi, H. Durani, T. Hölting, U. Amann, F. Kreuziger, T. Assmann, H. Brüning, L. Freitag, K. Hoffmann, R. Gedschold   +18 more
wiley   +1 more source

Managing Fractured Ceramic Restorations: Current Evidence and Best Practices—A Scoping Review

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective This scoping review aims to assess the effect of different protocols on the outcome of ceramic restoration repairs. Materials and Methods An electronic search was conducted in three databases (PubMed, Cochrane Library, and Embase), up to July 31st 2025, with previously identified MeSH terms. Results Out of the 2423 records, title and
Gabriela Almeida, Joana A. Marques, Markus B. Blatz, Rui I. Falacho   +3 more
wiley   +1 more source

Ozonized Hydrogel and Chlorhexidine Gel for Peri‐Implant Mucositis: A 24‐Month Randomized Controlled Trial

Oral Diseases, EarlyView.
ABSTRACT Objective This randomized controlled trial evaluated the 24‐month effectiveness of a nonsurgical intervention for peri‐implant mucositis, comparing a 15% ozonated sunflower oil hydrogel with a 1% chlorhexidine gel. Methods Thirty patients with 360 peri‐implant mucositis sites were treated in a split‐mouth design, receiving both therapies in ...
Andrea Scribante, Maurizio Pascadopoli, Matteo Pellegrini, Marco Saturnino Lupi, Carlos Pérez‐Albacete Martínez, Andrea Butera   +5 more
wiley   +1 more source

Possibility intraoperative photodynamic therapy in treatment of nоn-smoll lung cancer

RUDN Journal of Medicine, 2010
This work is devoted possibilities to use the intraoperative photodynamic therapy in treatment of nоn-small lung cancer. Studied the problem of calculate light-doses necessary for inactivation tumor-cells in pleural cavities.
S A Aminodov, M L Gelfond
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