Results 1 to 10 of about 156,894 (246)

Photodynamic Therapy

Biomedicines, 2022
In 1903, Von Tappeiner and Jesionek [...]
Kyungsu Kang, Stefano Bacci
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Photodynamic Therapy in Combination with Doxorubicin Is Superior to Monotherapy for the Treatment of Lung Cancer

Biomedicines, 2022
We have previously shown that a radioactive (123I)-analog of methyl 3-(1′-(iodobexyloxy) ethyl-3-devinylpyropheophorbide-a (PET-ONCO), derived from chlorophyll-a can be used for positron emission tomography (PET) imaging of a variety of tumors, including
Joseph C. Cacaccio, Farukh A. Durrani, Joseph R. Missert, Ravindra K. Pandey   +3 more
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First-In-Human Computer-Optimized Endobronchial Ultrasound-Guided Interstitial Photodynamic Therapy for Patients With Extrabronchial or Endobronchial Obstructing Malignancies

JTO Clinical and Research Reports, 2022
Objective: Patients with inoperable extrabronchial or endobronchial tumors who are not candidates for curative radiotherapy have dire prognoses with no effective long-term treatment options. To reveal that our computer-optimized interstitial photodynamic
Nathaniel M. Ivanick, MD, Emily R. Oakley, PhD, Rajesh Kunadharaju, MD, Craig Brackett, PhD, David A. Bellnier, PhD, Lawrence M. Tworek, BS, Sergei N. Kurenov, MS, Sandra O. Gollnick, PhD, Alan D. Hutson, PhD, Theresa M. Busch, PhD, Gal Shafirstein, DSc   +10 more
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A Remarkable Difference in Pharmacokinetics of Fluorinated Versus Iodinated Photosensitizers Derived from Chlorophyll-a and a Direct Correlation between the Tumor Uptake and Anti-Cancer Activity

Molecules, 2023
To investigate and compare the pharmacokinetic profile and anti-cancer activity of fluorinated and iodinated photosensitizers (PSs), the 3-(1′-(o-fluorobenzyloxy)ethyl pyropheophorbide and the corresponding meta-(m-) and para (p-) fluorinated analogs ...
Taur Prakash Pandurang, Joseph Cacaccio, Farukh A. Durrani, Mykhaylo Dukh, Ajyal Z. Alsaleh, Munawwar Sajjad, Francis D’Souza, Dalip Kumar, Ravindra K. Pandey   +8 more
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Ablative Fractional Laser Enhances Artificial or Natural Daylight Photodynamic Therapy of Actinic Field Cancerization: A Randomized and Investigator-initiated Half-side Comparative Study

Acta Dermato-Venereologica, 2023
Artificial daylight photodynamic therapy is a near-painless treatment for actinic keratoses, which can be performed indoors using a controlled light dose. Daylight photodynamic therapy is approved only for treatment of grade I–II actinic keratoses.
Vivian Lindholm, Mari Salmivuori, Sonja Hahtola, Kerttu Mäkelä, Sari Pitkänen, Kirsi Isoherranen   +5 more
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Targeted Nanoparticles for Fluorescence Imaging of Folate Receptor Positive Tumors

Biomolecules, 2020
This report presents the synthesis and folate receptor target-specificity of amino-functionalized polyacrylamide nanoparticles (AFPAA NPs) for near-infrared (NIR) fluorescence imaging of cancer. For the synthesis of desired nano-constructs, the AFPAA NPs
Aimee J. Marko, Ballav M. Borah, Kevin E. Siters, Joseph R. Missert, Anurag Gupta, Paula Pera, Meden F. Isaac-Lam, Ravindra K. Pandey   +7 more
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Pulsed Dye Laser-mediated Photodynamic Therapy is Less Effective than Conventional Photodynamic Therapy for Actinic Field Cancerization: A Randomized Half-side Comparative Study

Acta Dermato-Venereologica, 2021
Previous research presents pulsed dye laser-mediated photodynamic therapy as a promising alternative to conventional red-light photodynamic therapy. In this study, 60 patients with 2 or more actinic keratoses randomly received either of these treatments ...
Vivian Lindholm, Sari Pitkänen, Marika Schröder, Sonja Hahtola, Helka Sahi, Heini Halme, Kirsi Isoherranen   +6 more
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In Vivo Antitumoral Effects of Linseed Oil and Its Combination With Doxorubicin

Frontiers in Pharmacology, 2022
Linseed oil (LO) is known for its exceptional nutritional value due to the high content of alpha-linolenic acid (ALA), an essential omega-3 polyunsaturated fatty acid; its anticarcinogenic effect has been established in several experimental and ...
Oleg Shadyro, Oleg Shadyro, Anna Sosnovskaya, Irina Edimecheva, Lana Ihnatovich, Lana Ihnatovich, Boris Dubovik, Sergei Krasny, Dmitry Tzerkovsky, Egor Protopovich   +9 more
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Photodynamic Therapy for Treatment of Disease in Children—A Review of the Literature

Children, 2022
Photodynamic therapy is a mode of treatment whereby local irradiation of an administered photosensitizer with light of a specific wavelength generates cytotoxic reactive oxygen species. Despite the upward trend in the popularity of this method in adults,
Anna Mazur, Katarzyna Koziorowska, Klaudia Dynarowicz, David Aebisher, Dorota Bartusik-Aebisher   +4 more
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Photodynamic Therapy [PDF]

JNCI Journal of the National Cancer Institute, 1998
Photodynamic therapy involves administration of a tumor-localizing photosensitizing agent, which may require metabolic synthesis (i.e., a prodrug), followed by activation of the agent by light of a specific wavelength. This therapy results in a sequence of photochemical and photobiologic processes that cause irreversible photodamage to tumor tissues ...
T J, Dougherty, C J, Gomer, B W, Henderson, G, Jori, D, Kessel, M, Korbelik, J, Moan, Q, Peng   +7 more
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