Results 1 to 10 of about 4,660,211 (356)

Photodynamic therapy of cancer: An update

Ca-A Cancer Journal for Clinicians, 2011
Photodynamic therapy (PDT) is a clinically approved, minimally invasive therapeutic procedure that can exert a selective cytotoxic activity toward malignant cells.
Patrizia M Agostinis, Kristian Berg, Keith A Cengel   +2 more
exaly   +2 more sources

Photodynamic Therapy for Esophageal cancer

Canadian Journal of Gastroenterology, 1990
In photodynamic therapy, a photosensitizing drug is injected and then activated by light in the red spectral region to produce reactive, highly toxic singlet oxygen, which causes cell tissue and damage.
R Lambert
doaj   +2 more sources

Photodynamic Therapy in Combination with Doxorubicin Is Superior to Monotherapy for the Treatment of Lung Cancer

Biomedicines, 2022
We have previously shown that a radioactive (123I)-analog of methyl 3-(1′-(iodobexyloxy) ethyl-3-devinylpyropheophorbide-a (PET-ONCO), derived from chlorophyll-a can be used for positron emission tomography (PET) imaging of a variety of tumors, including
Joseph C. Cacaccio, Farukh A. Durrani, Joseph R. Missert, Ravindra K. Pandey   +3 more
doaj   +1 more source

The Current Status of Photodynamic Therapy in Cancer Treatment

Cancers, 2023
Simple Summary Photodynamic therapy (PDT), a non-invasive cancer treatment strategy, has presented a broad scope in future clinical applications.
Wenqi Jiang, Mingkang Liang, Qifang Lei, Guangzhi Li, Song Wu   +4 more
semanticscholar   +1 more source

First-In-Human Computer-Optimized Endobronchial Ultrasound-Guided Interstitial Photodynamic Therapy for Patients With Extrabronchial or Endobronchial Obstructing Malignancies

JTO Clinical and Research Reports, 2022
Objective: Patients with inoperable extrabronchial or endobronchial tumors who are not candidates for curative radiotherapy have dire prognoses with no effective long-term treatment options. To reveal that our computer-optimized interstitial photodynamic
Nathaniel M. Ivanick, MD, Emily R. Oakley, PhD, Rajesh Kunadharaju, MD, Craig Brackett, PhD, David A. Bellnier, PhD, Lawrence M. Tworek, BS, Sergei N. Kurenov, MS, Sandra O. Gollnick, PhD, Alan D. Hutson, PhD, Theresa M. Busch, PhD, Gal Shafirstein, DSc   +10 more
doaj   +1 more source

A Remarkable Difference in Pharmacokinetics of Fluorinated Versus Iodinated Photosensitizers Derived from Chlorophyll-a and a Direct Correlation between the Tumor Uptake and Anti-Cancer Activity

Molecules, 2023
To investigate and compare the pharmacokinetic profile and anti-cancer activity of fluorinated and iodinated photosensitizers (PSs), the 3-(1′-(o-fluorobenzyloxy)ethyl pyropheophorbide and the corresponding meta-(m-) and para (p-) fluorinated analogs ...
Taur Prakash Pandurang, Joseph Cacaccio, Farukh A. Durrani, Mykhaylo Dukh, Ajyal Z. Alsaleh, Munawwar Sajjad, Francis D’Souza, Dalip Kumar, Ravindra K. Pandey   +8 more
doaj   +1 more source

Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments

Medicinal research reviews (Print), 2023
Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial infections. This treatment dates back to 1900 when a German medical school graduate Oscar Raab found a photodynamic effect while doing research for his doctoral ...
Markéta Kolaříková, B. Hošíková, Hanna Dilenko, Katerina Barton-Tomankova, L. Válková, R. Bajgar, L. Malina, H. Kolářová   +7 more
semanticscholar   +1 more source

Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy

Theranostics, 2022
Cancer immunotherapy has made tremendous clinical progress in advanced-stage malignancies. However, patients with various tumors exhibit a low response rate to immunotherapy because of a powerful immunosuppressive tumor microenvironment (TME) and ...
Bin Ji, Minjie Wei, Bin Yang
semanticscholar   +1 more source

Ablative Fractional Laser Enhances Artificial or Natural Daylight Photodynamic Therapy of Actinic Field Cancerization: A Randomized and Investigator-initiated Half-side Comparative Study

Acta Dermato-Venereologica, 2023
Artificial daylight photodynamic therapy is a near-painless treatment for actinic keratoses, which can be performed indoors using a controlled light dose. Daylight photodynamic therapy is approved only for treatment of grade I–II actinic keratoses.
Vivian Lindholm, Mari Salmivuori, Sonja Hahtola, Kerttu Mäkelä, Sari Pitkänen, Kirsi Isoherranen   +5 more
doaj   +1 more source

Photodynamic Therapy Review: Principles, Photosensitizers, Applications, and Future Directions

Pharmaceutics, 2021
Photodynamic therapy (PDT) is a minimally invasive therapeutic modality that has gained great attention in the past years as a new therapy for cancer treatment.
J. Correia, J. A. Rodrigues, S. Pimenta, T. Dong, Zhaochu Yang   +4 more
semanticscholar   +1 more source