Results 1 to 10 of about 79,111 (306)

Photodynamic Therapy in Combination with Doxorubicin Is Superior to Monotherapy for the Treatment of Lung Cancer

open access: yesBiomedicines, 2022
We have previously shown that a radioactive (123I)-analog of methyl 3-(1′-(iodobexyloxy) ethyl-3-devinylpyropheophorbide-a (PET-ONCO), derived from chlorophyll-a can be used for positron emission tomography (PET) imaging of a variety of tumors, including
Joseph C. Cacaccio   +3 more
doaj   +1 more source

A Remarkable Difference in Pharmacokinetics of Fluorinated Versus Iodinated Photosensitizers Derived from Chlorophyll-a and a Direct Correlation between the Tumor Uptake and Anti-Cancer Activity

open access: yesMolecules, 2023
To investigate and compare the pharmacokinetic profile and anti-cancer activity of fluorinated and iodinated photosensitizers (PSs), the 3-(1′-(o-fluorobenzyloxy)ethyl pyropheophorbide and the corresponding meta-(m-) and para (p-) fluorinated analogs ...
Taur Prakash Pandurang   +8 more
doaj   +1 more source

Targeted Nanoparticles for Fluorescence Imaging of Folate Receptor Positive Tumors

open access: yesBiomolecules, 2020
This report presents the synthesis and folate receptor target-specificity of amino-functionalized polyacrylamide nanoparticles (AFPAA NPs) for near-infrared (NIR) fluorescence imaging of cancer. For the synthesis of desired nano-constructs, the AFPAA NPs
Aimee J. Marko   +7 more
doaj   +1 more source

Ablative Fractional Laser Enhances Artificial or Natural Daylight Photodynamic Therapy of Actinic Field Cancerization: A Randomized and Investigator-initiated Half-side Comparative Study

open access: yesActa Dermato-Venereologica, 2023
Artificial daylight photodynamic therapy is a near-painless treatment for actinic keratoses, which can be performed indoors using a controlled light dose. Daylight photodynamic therapy is approved only for treatment of grade I–II actinic keratoses.
Vivian Lindholm   +5 more
doaj   +1 more source

Pulsed Dye Laser-mediated Photodynamic Therapy is Less Effective than Conventional Photodynamic Therapy for Actinic Field Cancerization: A Randomized Half-side Comparative Study

open access: yesActa Dermato-Venereologica, 2021
Previous research presents pulsed dye laser-mediated photodynamic therapy as a promising alternative to conventional red-light photodynamic therapy. In this study, 60 patients with 2 or more actinic keratoses randomly received either of these treatments ...
Vivian Lindholm   +6 more
doaj   +1 more source

In Vivo Antitumoral Effects of Linseed Oil and Its Combination With Doxorubicin

open access: yesFrontiers in Pharmacology, 2022
Linseed oil (LO) is known for its exceptional nutritional value due to the high content of alpha-linolenic acid (ALA), an essential omega-3 polyunsaturated fatty acid; its anticarcinogenic effect has been established in several experimental and ...
Oleg Shadyro   +9 more
doaj   +1 more source

Photodynamic Therapy for Esophageal Cancer [PDF]

open access: yesClinical Endoscopy, 2021
Photodynamic therapy, a curative local treatment for esophageal squamous cell carcinoma, involves a photosensitizing drug (photosensitizer) with affinity for tumors and a photodynamic reaction triggered by laser light.
Takahiro Inoue, Ryu Ishihara
doaj   +1 more source

Photodynamic Therapy for Treatment of Disease in Children—A Review of the Literature

open access: yesChildren, 2022
Photodynamic therapy is a mode of treatment whereby local irradiation of an administered photosensitizer with light of a specific wavelength generates cytotoxic reactive oxygen species. Despite the upward trend in the popularity of this method in adults,
Anna Mazur   +4 more
doaj   +1 more source

TLD1433-Mediated Photodynamic Therapy with an Optical Surface Applicator in the Treatment of Lung Cancer Cells In Vitro

open access: yesPharmaceuticals, 2020
Intra-operative photodynamic therapy (IO-PDT) in combination with surgery for the treatment of non-small cell lung cancer and malignant pleural mesothelioma has shown promise in improving overall survival in patients.
Sarah Chamberlain   +5 more
doaj   +1 more source

Sonodynamic therapy in combination with photodynamic therapy shows enhanced long-term cure of brain tumor

open access: yesScientific Reports, 2020
This article presents the construction of a multimodality platform that can be used for efficient destruction of brain tumor by a combination of photodynamic and sonodynamic therapy.
Ballav M. Borah   +6 more
doaj   +1 more source

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