Results 31 to 40 of about 51,866 (257)

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Susceptibility and Resistance Mechanisms During Photodynamic Therapy of Melanoma

Frontiers in Oncology, 2020
Melanoma is the most aggressive malignant skin tumor and arises from melanocytes. The resistance of melanoma cells to various treatments results in rapid tumor growth and high mortality.
Xin-Ying Li, Liu-Chang Tan, Li-Wen Dong, Wan-Qi Zhang, Xiao-Xiao Shen, Xiao Lu, Hong Zheng, Yuan-Gang Lu   +7 more
doaj   +1 more source

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

Advanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

Photodynamic Therapy in Gastroenterology

Journal of Gastrointestinal Cancer, 2013
Photodynamic therapy (PDT) is a minimally invasive and promising new modality to combat cancer. Upon illumination and in the presence of oxygen, the tissue-localized nontoxic sensitizer generates cytotoxic reactive oxygen species, and as a result, the selective destruction of a targeted tumor may be achieved.
Shishkova N., Kuznetsova O., Berezov T.
openaire   +5 more sources

Nanoplatforms for Sentinel and Tumor‐Draining Lymph Node Mapping: From Visualization to Pathway‐Informed Staging

Advanced Healthcare Materials, EarlyView.
Lymphotropic nanoplatforms integrate multimodal imaging with therapeutic guidance to map sentinel and tumor‐draining lymph nodes, revealing functional drainage, metastatic involvement, and nodal accessibility, while providing mechanistic insight to support precision surgical and therapeutic interventions.
Xu Chen, Nina Li, Meiyan Zou, Zihao Zhou, Rongwei Xu, Weiyao Feng, Xinyuan Zhao, Li Cui   +7 more
wiley   +1 more source

Gold Nanorod-Decorated Metallic MoS₂ Nanosheets for Synergistic Photothermal and Photodynamic Antibacterial Therapy

Nanomaterials, 2021
Light-responsive nanocomposites have become increasingly attractive in the biomedical field for antibacterial applications. Visible-light-activated metallic molybdenum disulfide nanosheets (1T-MoS2 NSs) and plasmonic gold nanorods (AuNRs) with absorption
Sibidou Yougbaré, Chinmaya Mutalik, Pei-Feng Chung, Dyah Ika Krisnawati, Fajar Rinawati, Hengky Irawan, Heny Kristanto, Tsung-Rong Kuo   +7 more
doaj   +1 more source

Rational Design of Organic Chromophores for Simultaneously Trig‐gering Redox Imbalance and Tracking Organelles in Biological Sys‐tems Under Near‐Infrared Light Irradiation

Advanced Healthcare Materials, EarlyView.
TOC represents the synthesis of theory‐guided novel near‐infrared (NIR) light‐absorbing organic photosensitizers (OPS) enabling redox‐induced tumor phototherapy and single‐cell organelle tracking. ABSTRACT The design of organic photosensitizers that operate efficiently in the near‐infrared (NIR) region remains challenging due to the need to balance ...
Pragti, Bidyut Kumar Kundu, Jiajie Diao, Yujie Sun   +3 more
wiley   +1 more source

Exploring Patient Pain Experiences during and after Conventional Red Light and Simulated Daylight Photodynamic Therapy for Actinic Keratosis: A Qualitative Interview Study

Acta Dermato-Venereologica
Simulated daylight photodynamic therapy is a relatively new and potentially less painful alternative to conventional red light photodynamic therapy for actinic keratosis.
Alexandra Sjöholm, Magdalena Claeson, John Paoli, Birgit Heckemann   +3 more
doaj   +1 more source

Histopathological Analysis of the Effect of Photodynamic Action on Post-Chemotherapy Excised Breast Cancer Tissue

Medicina, 2022
Background and objectives: Breast cancer is the most commonly diagnosed cancer in women and its mortality is increasing. Therefore, research to improve treatment is of paramount importance. One method of treatment is photodynamic therapy.
Elżbieta Ostańska, Edyta Barnaś, Dorota Bartusik-Aebisher, Klaudia Dynarowicz, Magdalena Szpunar, Joanna Skręt-Magierło, David Aebisher   +6 more
doaj   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source