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Dermatologic Clinics, 2014
Photodynamic therapy (PDT) relies on the interaction between a photosensitizer, the appropriate wavelength, and oxygen to cause cell death. First introduced about 100 years ago, PDT has continued to evolve in dermatology into a safe and effective treatment option for several dermatologic conditions.
Ali M, Rkein, David M, Ozog
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Photodynamic therapy (PDT) relies on the interaction between a photosensitizer, the appropriate wavelength, and oxygen to cause cell death. First introduced about 100 years ago, PDT has continued to evolve in dermatology into a safe and effective treatment option for several dermatologic conditions.
Ali M, Rkein, David M, Ozog
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Photochemistry and Photobiology, 1985
Photodynamic therapy for treatment of malignant tumors uses certain porphyrins as relatively tumor-selective photosensitizers. A wide variety of tumors take up and retain these materials, which can result in complete eradication of the local tumor provided that light of the proper wavelength and sufficient dose is used.
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Photodynamic therapy for treatment of malignant tumors uses certain porphyrins as relatively tumor-selective photosensitizers. A wide variety of tumors take up and retain these materials, which can result in complete eradication of the local tumor provided that light of the proper wavelength and sufficient dose is used.
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Advances in Dermatology, 2006
ALA-PDT is a safe, well-tolerated, and effective treatment for many dermatologic conditions. Current data most strongly support its use in the treatment of actinic damage, but further investigation into alternative uses continues. Current efficacy is limited primarily by the depth of penetration of the photosensitizing agent and the activating light ...
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ALA-PDT is a safe, well-tolerated, and effective treatment for many dermatologic conditions. Current data most strongly support its use in the treatment of actinic damage, but further investigation into alternative uses continues. Current efficacy is limited primarily by the depth of penetration of the photosensitizing agent and the activating light ...
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Gastrointestinal Endoscopy Clinics of North America, 2011
Photodynamic therapy (PDT) is a photochemical process that uses a photosensitizer drug activated by laser light to produce mucosal ablation. Porfimer sodium PDT has proved long-term efficacy and durability in the treatment of Barrett's esophagus and high-grade dysplasia and early esophageal adenocarcinoma.
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Photodynamic therapy (PDT) is a photochemical process that uses a photosensitizer drug activated by laser light to produce mucosal ablation. Porfimer sodium PDT has proved long-term efficacy and durability in the treatment of Barrett's esophagus and high-grade dysplasia and early esophageal adenocarcinoma.
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Innovative therapies: photodynamic therapy
Thoracic Surgery Clinics, 2004Photodynamic diagnosis could be a useful tool for improving the diagnostic yield of tumor biopsy, especially for mesothelioma tumors that are sclerotic and particularly hypocellular. For PDD, the use of low doses of a sensitizing drug, such as 5-ALA, must be investigated further. The initial results of 5-ALA-mediated PDD are promising. The role, if any,
Evelio, Rodriguez +2 more
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Photosensitizers for Photodynamic Therapy
Advanced Healthcare Materials, 2019AbstractAs an emerging clinical modality for cancer treatment, photodynamic therapy (PDT) takes advantage of the cytotoxic activity of reactive oxygen species (ROS) that are generated by light irradiating photosensitizers (PSs) in the presence of oxygen (O2).
Minhuan Lan +5 more
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Photodynamic Therapy in Gynecology
Obstetrics and Gynecology Clinics of North America, 1991PDT is a technique in which visible light is used in combination with photosensitizing agents to achieve a tumoricidal effect. Hematoporphyrins are the most commonly used photosensitizers in clinical practice. DHE is the active fraction of hematoporphyrin. Intravenously injected DHE is found in highest concentration in the liver followed by the spleen,
M, Spitzer, B A, Krumholz
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Photodynamic Therapy in Dermatology
Archives of Dermatology, 1998Photodynamic therapy (PDT) uses exogenously administered or endogenously formed photosensitizers activated by light to induce cell death via formation of singlet oxygen and other free radicals. Photodynamic therapy is increasingly used for the treatment of skin cancers and other indications.
C, Fritsch, G, Goerz, T, Ruzicka
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Photodynamic therapy in dermatology
Journal of the American Academy of Dermatology, 2000The combination of light and chemicals to treat skin diseases is widely practiced in dermatology. Within this broad use of light and drugs, in recent years the concept of photodynamic therapy (PDT) has emerged. PDT is a promising modality for the management of various tumors and nonmalignant diseases, based on the combination of a photosensitizer that ...
K, Kalka, H, Merk, H, Mukhtar
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Dermatology, 2007
<i>Background:</i> Photodynamic therapy (PDT) is increasingly used in the treatment of various skin diseases. The main adverse effect in PDT treatment is pain. Each lesion is generally treated twice, and clinical experience suggests that the 2nd treatment causes more pain than the 1st and thus becomes a therapy-limiting factor.
Katrine E K, Lindeburg +2 more
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<i>Background:</i> Photodynamic therapy (PDT) is increasingly used in the treatment of various skin diseases. The main adverse effect in PDT treatment is pain. Each lesion is generally treated twice, and clinical experience suggests that the 2nd treatment causes more pain than the 1st and thus becomes a therapy-limiting factor.
Katrine E K, Lindeburg +2 more
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