Results 61 to 70 of about 90,404 (262)

Spatiotemporally Ultrasound‐Controlled Nanoparticles Reprogramming Immunostimulatory Antigen‐Presenting Cancer‐Associated Fibroblasts to Enhance Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai   +9 more
wiley   +1 more source

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

open access: yesAdvanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li   +10 more
wiley   +1 more source

ANÁLISE DE AMOSTRAS DE COMBUSTÍVEIS POR FOTOMETRIA, NIR PORTÁTIL E RMN DE 1H - UMA COMPARAÇÃO COM OS RESULTADOS ENCONTRADOS POR TÉCNICAS NORMATIZADAS

open access: yesQuímica Nova
It has been recurring adulterations in fuels (such as gasoline, ethanol and diesel), being necessary the exploration of the use of more modern analytical techniques capable of controlling the quality of these fuels, since some regulated tests may be ...
Flavia Tosato   +14 more
doaj   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

open access: yesAdvanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li   +8 more
wiley   +1 more source

More Efficient and Reliable: Identifying RRab Stars with Blazhko Effect by Deep Convolutional Neural Network

open access: yesUniverse
The physical origin of the Blazhko effect (BL), a phenomenon of a single or multiple periodic modulation(s) of the light curve, is under debate. Efficiently identifying and characterizing the BL is essential in understanding its origins and accounting ...
Nan Jiang   +6 more
doaj   +1 more source

The Development of Stellar Photometry in Russia and the USSR in the 20Th Century (Some Pages of History)

open access: yesOpen Astronomy, 2003
A short historical review of the development of astrophotometry in Russia and the Soviet Union is given. The input of V. Cerasky, G. Tikhov, V. B. Nikonov, Moscow University astronomers and Vilnius astronomers is described.
Mironov A. V.
doaj   +1 more source

Deep Photometric Stereo Network with Multi-Scale Feature Aggregation

open access: yesSensors, 2020
We present photometric stereo algorithms robust to non-Lambertian reflection, which are based on a convolutional neural network in which surface normals of objects with complex geometry and surface reflectance are estimated from a given set of an ...
Chanki Yu, Sang Wook Lee
doaj   +1 more source

Constraining dark energy using real and mock galaxy surveys [PDF]

open access: yes, 2009
In this thesis, we study how dark energy may be constrained by measurements of large-scale clustering in future galaxy surveys, and through the imprint of a time-varying large-scale potential on the CMB (the integrated Sachs-Wolfe effect).
CAI, YANCHUAN
core  

Classification of Metal-Deficient Dwarfs in the Vilnius Photometric System

open access: yesOpen Astronomy, 2003
Methods used for the quantitative classification of metal-deficient stars in the Vilnius photometric system are reviewed. We present a new calibration of absolute magnitudes for dwarfs and subdwarfs, based on Hipparcos parallaxes.
Lazauskaitė R.   +2 more
doaj   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

open access: yesAdvanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang   +7 more
wiley   +1 more source

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