Results 51 to 60 of about 64,417 (247)

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

open access: yesAdvanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou   +10 more
wiley   +1 more source

Hydrogen-rich to stripped-envelope: observational continuity and biases in CCSNe

open access: yesFrontiers in Astronomy and Space Sciences
Although historically classified into discrete subclasses, there is growing evidence that indicates that core-collapse supernovae (CCSNe) categories often overlap, reflecting continuous variations in progenitor structure, mass-loss history, and ...
Anjasha Gangopadhyay   +2 more
doaj   +1 more source

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

open access: yesAdvanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li   +10 more
wiley   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

open access: yesAdvanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang   +7 more
wiley   +1 more source

AS 314: A Massive Dusty Hypergiant or a Low-Mass Post-Asymptotic Giant Branch Object?

open access: yesGalaxies
AS 314 (V452 Sct) is a poorly studied early-type emission-line star, which exhibits an infrared excess at wavelengths longer than 10 μm. Its earlier studies have been limited to small amounts of observational data and led to controversial conclusions ...
Aigerim Bakhytkyzy   +8 more
doaj   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

open access: yesAdvanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu   +16 more
wiley   +1 more source

High precision ground-based CCD photometry from the Next Generation Transit Survey [PDF]

open access: yes, 2022
The Next Generation Transit Survey (NGTS) has now been operating for six years, discovering and characterizing transiting exoplanets around bright stars.
Smith, Alexis M. S.   +32 more
core   +1 more source

New Light Curves and Orbital Period Investigations of the Interacting Binary System UV Piscium

open access: yesJournal of Astronomy and Space Sciences, 2019
UV Psc is a typical RS CVn type system undergoing dynamic chromosphere activity. We performed photometric observations of the system in 2015 and secured new BVR light curves showing well-defined photometric waves.
Min-Ji Jeong   +2 more
doaj   +1 more source

Rainfall Shapes the Diversity of Soil Nitrogen‐Fixing Microorganisms Worldwide

open access: yesAdvanced Science, EarlyView.
This study reveals the distinctive pattern and mechanism of rainfall driving the global biodiversity and biogeography of soil potential N‐fixing microorganisms, and constructs the theoretical framework. The results guide us on how to maintain ecosystem productivity under future climate changes (e.g., whether a specific region needs more N fertilizers ...
Bin Hua   +18 more
wiley   +1 more source

The near-core rotation of HD 112429: a gamma Doradus star with TESS photometry and legacy spectroscopy

open access: yes, 2022
The TESS space mission provides us with high-precision photometric observations of bright stars over more than 70% of the entire sky, allowing us to revisit and characterise well-known stars.
Prat, V.   +29 more
core   +1 more source

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