Results 91 to 100 of about 308,461 (247)

Estrogen Alleviates Sevoflurane‐Induced Neurotoxicity by Inhibiting ERα‐Tau Binding

open access: yesAdvanced Science, EarlyView.
Sevoflurane‐induced neurotoxicity exhibits sex differences, and estrogen can mitigate these effects; however, its protective action appears to be time‐window dependent, which may be related to the competitive binding of estrogen and Tau to ERα. Abstract Sevoflurane‐induced neurotoxicity is age‐dependent, but the role of sex differences is unclear ...
Feixiang Li   +8 more
wiley   +1 more source

New Astronomical Observatory Design for the Detection and Tracking of Satellite Objects: The Satellite Robotic Observatory (SRO)

open access: yesRemote Sensing
Robotic Astronomical Observatories (RAOs) have provided very good results in different research projects in astrophysics/astronomy. Their applications in the detection, tracking, and identification of near-Earth objects have contributed to the ...
Francisco Espartero   +3 more
doaj   +1 more source

Resolving Stellar Populations outside the Local Group: MAD observations of UKS2323-326 [PDF]

open access: yes, 2008
We present a study aimed at deriving constraints on star formation at intermediate ages from the evolved stellar populations in the dwarf irregular galaxy UKS2323-326.
A. Baruffolo   +40 more
core   +1 more source

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

open access: yesAdvanced Science, EarlyView.
cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang   +14 more
wiley   +1 more source

Optical Multicolor Photometry of Spectrophotometric Standard Stars

open access: yesThe Astronomical Journal, 2007
76 pages, 48 figures - published version available here: http://www.journals.uchicago.edu/AJ/journal/issues/v133n3/205588/205588.html .
Arlo U. Landolt   +4 more
openaire   +3 more sources

Flickers, Bursts, and Dips: Detecting Rapid Variability with the g(2) Autocorrelation Function

open access: yesThe Astrophysical Journal
Rapid optical transient events can be hard to detect because of the limited number of photons they produce. I discuss a method of inferring the presence of fast, chaotic variability in photometry using the normalized autocorrelation function, what is ...
Brian C. Lacki
doaj   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

open access: yesAdvanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang   +19 more
wiley   +1 more source

JWST Imaging of the Closest Globular Clusters—VI. The Lowest‐Mass Objects in M 4 and the Galactic Bulge

open access: yesAstronomische Nachrichten, EarlyView.
ABSTRACT We present James Webb Space Telescope observations of M 4—the closest globular cluster—that probe the lower Main Sequence down to the hydrogen‐burning limit. The unveiled stellar sequence reaches much fainter luminosities than previously possible, revealing a few extremely red objects that are consistent with brown dwarfs as cool as Teff∼1000K$
L. R. Bedin   +10 more
wiley   +1 more source

Discovery of two L & T binaries with wide separations and peculiar photometric properties

open access: yes, 2011
We present spatially resolved photometric and spectroscopic observations of two wide brown dwarf binaries uncovered by the SIMP near-infrared proper motion survey.
Allen   +62 more
core   +2 more sources

A novel treatment of biogas digestate waste for biochar production and its adsorption of methylene blue and malachite green in a binary system

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract This study presents a novel treatment of biogas digestate to produce biochar at processing temperatures of 500–700 °C. The resulting biochar was applied for the simultaneous removal of methylene blue (MB) and malachite green (MG) in a binary system.
Van Hau Duong   +10 more
wiley   +1 more source

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