Results 31 to 40 of about 11,034 (258)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Application of photon-counting CT in cardiovascular diseases [PDF]

Zhenduanxue lilun yu shijian
Photon-counting computed tomography （PCCT） is a revolutionary technological breakthrough in CT imaging over the past decade. Compared with traditional energy-integrating detector CT, PCCT performs imaging at the single-photon level at the detector layer,
WANG Mengzhen, BAO Shouyu, LIU Peng, YAN Fuhua, YANG Wenjie
doaj   +1 more source

Response Properties of Silicon Trench Photodiodes to Single α- and γ-Ray in Pulse Mode

IEEE Access, 2022
This study proposes a new silicon X-ray sensor structure for photon-counting computed tomography (CT), which is a next-generation low-dose X-ray imaging technique.
Tetsuya Ariyoshi
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Charge Generation and Recombination Pathways in All‐Polymer Bulk Heterojunction Solar Cells

Advanced Functional Materials, EarlyView.
Multimodal spectroscopy and device analysis reveal how field‐dependent charge generation, transport limitations, and non‐geminate recombination govern performance losses in all polymer solar cells. The results identify the key processes controlling charge extraction and recombination, providing insights for the design of more efficient all‐polymer ...
Shahidul Alam, Wejdan Althobaiti, Safakath Karuthedath, Christopher E. Petoukhoff, Amr Dahman, Khawla Alkhezaim, Oleksandr Matiash, José P. Jurado, Mariia Ferree, Ning Su, Jacob Blaskovits, Denis Andrienko, Vladimir Dyakonov, Andreas Sperlich, Vojtech Nádaždy, Tobin J. Marks, Antonio Facchetti, Frédéric Laquai   +17 more
wiley   +1 more source

Investigating Image Distortion and Its Impact on Material Quantification in Photon-counting Computed Tomography

Journal of Medical Physics
Background: Photon-counting computed tomography (PCCT) enables simultaneous spatial and spectral imaging for improved material discrimination. However, inaccuracies in scanner geometric calibration can introduce reconstruction distortions that degrade ...
Rayhan Uddin, Marzieh Anjomrouz, Neryda Duncan, Anthony Butler, Philip Butler   +4 more
doaj   +1 more source

Development of Multifunctional Hierarchically Restructured Antibacterial Neural Interfacing Electrodes via Plasma‐Enhanced Atomic Layer Deposition of Zinc Oxide Thin Films

Advanced Functional Materials, EarlyView.
ABSTRACT Next‐generation implantable neural‐interfacing devices are increasingly constrained by the coupled demands of electrode miniaturization, electrochemical performance, and implantation infection risk. Femtosecond laser–based hierarchical surface restructuring (HSR) technology has emerged as a scalable, manufacturing‐compatible platform for ...
Henna Khosla, Wesley Seche, Kriti Panchal, Steven J. May, Ekaterina Pomerantseva, Jacob Elmer, Tyler Cooper, Matthew J. Urban, Hailey Y. Maurer, Gregory A. Caputo, Jeffrey Hettinger, Shahram Amini, Gang Feng   +12 more
wiley   +1 more source

Triple-source saddle-curve cone-beam photon counting CT image reconstruction: A simulation study

Zeitschrift für Medizinische Physik
Purpose: The most common detector material in the PC CT system, cannot achieve the best performance at a relatively higher photon flux rate. In the reconstruction view, the most commonly used filtered back projection, is not able to provide sufficient ...
Lin Xin, Weihai Zhuo, Qian Liu, Tianwu Xie, Habib Zaidi   +4 more
doaj   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

Advanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno, Qiangrui Dong, Marco Post, Xin Meng, Cristiano Glessi, Nynke Marije Hettema, Nidas Brandsma, Sebbe Blokhuizen, Alejandro Castañeda Garcia, Srividya Ganapathy, Thieme Schmidt, Lars van Roemburg, Bing Xu, Chun‐Ting Cho, Liedewij Laan, Miao‐Ping Chien, Daan Brinks   +16 more
wiley   +1 more source

Photon-Counting Micro-CT for Bone Morphometry in Murine Models

Tomography
Background/Objectives: This study evaluates photon-counting CT (PCCT) for the imaging of mouse femurs and investigates how APOE genotype, sex, and humanized nitric oxide synthase (HN) expression influence bone morphology during aging.
Rohan Nadkarni, Zay Yar Han, Alex J. Allphin, Darin P. Clark, Alexandra Badea, Cristian T. Badea   +5 more
doaj   +1 more source