Results 121 to 130 of about 1,646,093 (289)

Impact of reconstruction parameters on the accuracy of myocardial extracellular volume quantification on a first-generation, photon-counting detector CT

European Radiology Experimental
The potential role of cardiac computed tomography (CT) has increasingly been demonstrated for the assessment of diffuse myocardial fibrosis through the quantification of extracellular volume (ECV). Photon-counting detector (PCD)-CT technology may deliver
C. Gnasso, D. Pinos, U. Schoepf, M. Vecsey-Nagy, G. Aquino, N. Fink, Emese Zsarnóczay, Robert J. Holtackers, Jonathan Stock, P. Suranyi, Á. Varga-Szemes, T. Emrich   +11 more
semanticscholar   +1 more source

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

Advanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang, Xiaoyan Li, Yiran Liang, Yifei Wang, Yuhan Jin, Jianing Wang, Dan Luo, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Wenjing Zhao, Bing Chen, Lijuan Wang, Qifeng Yang   +16 more
wiley   +1 more source

Covalent Organic Framework Colloids With Core‐Shell Donor/Acceptor Architecture and Ultralong‐Lived Charge‐Separated States

Angewandte Chemie, EarlyView.
Uniform core‐shell colloidal particles of Covalent Organic Frameworks (COFs) are synthesized by a seeded growth of electron‐acceptor COF shells on electron‐donor COF cores. The resulting p‐n heterojunction enables efficient separation of photogenerated charges, which persist for minutes. These core‐shell COFs show efficient CO2 photoreduction to CO and
Ting Yu, Cory Ruchlin, Tong Li, Mohammad Hossein Gohari, Zhechang He, Zeina Chamseddine, Chang Wan Kang, Dongling Ma, Dmytro F. Perepichka   +8 more
wiley   +2 more sources

Photon Counting Computed Tomography for Accurate Cribriform Plate (Lamina Cribrosa) Imaging in Adult Patients

Tomography
Detailed visualization of the cribriform plate is challenging due to its intricate structure. This study investigates how computed tomography (CT) with a novel photon counting (PC) detector enhance cribriform plate visualization compared to traditionally
Anna Klempka, Eduardo Ackermann, Sven Clausen, Christoph Groden   +3 more
doaj   +1 more source

Fully Convolutional Pyramidal Residual Network for Material Discrimination of Spectral CT

IEEE Access, 2019
The spectral computed tomography (CT) based on photon-counting detector performs energy-dependent image reconstruction of material attenuation coefficients, allowing for effective medical diagnosis and material discrimination.
Zourong Long, Peng He, Xiaochuan Wu, Xiaodong Guo, Xuezhi Ren, Mianyi Chen, Jingxuan Gao, Biao Wei, Wenxiang Cong, Peng Feng   +9 more
doaj   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

TADF‐Active Tetrazole Luminophores for Visible‐Light Functionalization of Nanoparticles and Surfaces

Angewandte Chemie, EarlyView.
A series of tetrazoles are reported that undergo 1,3‐dipolar cycloadditions with alkene and alkyne substrates, generating (dihydro)pyrazole products that exhibit thermally activated delayed fluorescence (TADF). The “photo‐click” reactivity of these tetrazoles is leveraged to functionalize nanoparticles and surfaces with TADF‐active chromophores ...
Ryoga Hojo, Katrina Bergmann, Siyuan L. Xie, Connor S. Durfy, William L. Primrose, Athan T. Gogoulis, Seja A. Elgadi, Mitchell J. Demchuk, Thomas Kalab, Peiqi Hu, Eva M. Nichols, Zachary M. Hudson   +11 more
wiley   +2 more sources

Beam hardening of K-edge contrast agents: a phantom study comparing clinical energy-integrating detector and photon-counting detector CT systems

European Radiology Experimental
Background Beam hardening (BH) artifacts negatively influence computed tomography (CT) measurements, especially when due to dense materials or materials with high effective atomic numbers. Photon-counting detectors (PCD) are more susceptible to BH due to
Amir Pourmorteza, Arnaud Richard Choux, Thomas Wesley Holmes, U. Joseph Schoepf, Marly van Assen, Carlo De Cecco, Tilman Emrich, Akos Varga-Szemes   +7 more
doaj   +1 more source

Intracranial Calcification Detection; a Comparison Between Micro-CT, Conventional CT and Ultra-high-resolution Photon-Counting Detector CT.

Academic Radiology
RATIONALE AND OBJECTIVES To evaluate the performance of photon-counting detector CT (PCD-CT) in identifying and quantifying intracranial calcifications compared to conventional energy-integrating CT (EID-CT), utilizing micro-CT (µCT) as benchmark ...
J. van der Bie, Bernhard P. Berghout, R. Budde, Jose D. Gutierrez, M. van Straten, D. Bos   +5 more
semanticscholar   +1 more source

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source