Results 91 to 100 of about 2,714,943 (294)

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

open access: yesAdvanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi   +14 more
wiley   +1 more source

Elastomeric 3D‐Printed Microenvironments Enable Nanonewton Force Measurements in Healthy and Diseased Human Pluripotent Stem Cell‐Derived Neuroepithelial Cells

open access: yesAdvanced Materials, EarlyView.
We present elastomeric three‐dimensional (3D) microstructures fabricated via two‐photon polymerization (2PP) and post‐processed through wet etching, for quantifying nanonewton (nN)‐scale forces applied by healthy and diseased neural cells. The mechanically characterized free‐standing beam architectures enable measurement of traction forces of ...
Pieter F. J. van Altena   +7 more
wiley   +1 more source

Is proton beam therapy always better than photon irradiation? Lessons from two cases

open access: yesJournal of Medical Radiation Sciences
Proton beam therapy (PBT) is increasingly used to treat cancers, especially in the paediatric and adolescent and young adult (AYA) population. As PBT becomes more accessible, determining when PBT should be used instead of photon irradiation can be ...
Michelle P Li   +8 more
doaj   +1 more source

Journal of Proton Therapy: Call for Papers

open access: yes, 2015
Journal of Proton Therapy (JPT) is an international open access, peer-reviewed journal, which publishes original research, technical reports, reviews, case reports, editorials, and other materials on proton therapy with focus on radiation oncology ...
Proton Therapy, Journal of
core  

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Combining Two-Photon-Activated Fluorescence Resonance Energy Transfer and Near-Infrared Photothermal Effect of Unimolecular Micelles for Enhanced Photodynamic Therapy

open access: yes, 2016
Recent years have witnessed significant progress in the field of two-photon-activated photodynamic therapy (2P-PDT). However, the traditional photosensitizer (PS)-based 2P-PDT remains a critical challenge in clinics due to its low two-photon absorption ...
Deyue Yan (1315155)   +8 more
core   +1 more source

Two-photon-absorption-based OSNR monitor for NRZ-PSK transmission systems [PDF]

open access: yes, 2010
A two-photon absorption microcavity-based technique for monitoring in-band optical signal-to-noise ratio (OSNR) in nonreturn-to-zero phase-shift-keying systems is presented.
Guo, Wei Hua   +10 more
core   +1 more source

Photon-photon interaction mediated by a virtual photon in a nonlinear microcavity

open access: yes, 2023
Interactions between single photons play a crucial role in both fundamental physics and quantum technologies. So far, only a few demonstrations of photon interactions have been accomplished using quantum emitters that are strongly coupled to optical ...
Kejie Fang (11997542)   +1 more
core   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

open access: yesAdvanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian   +7 more
wiley   +1 more source

Toxicity profiles of proton and photon radiotherapy in postoperative breast cancer: a 10-year real-world cohort study

open access: yesBreast Cancer Research
Background Proton therapy, with its superior dose distribution, has emerged as a promising radiotherapy (RT) technique. This study evaluates the clinical benefits of proton therapy in reducing treatment-related toxicities in breast cancer patients ...
Chi-Chang Yu   +5 more
doaj   +1 more source

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