Results 191 to 200 of about 2,714,943 (294)

Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery

Advanced Science, EarlyView.
Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie, Jiahe Liu, Xiangyu Zhao, Siying Yang, Han Sun, Bingqian Jia, Xiaohong Ren, Xintao Chen, Lixin Sun, Li Wu, Caifen Wang, Jiwen Zhang   +11 more
wiley   +1 more source

Deep Learning-Based Synthetic CT for Personalized Treatment Modality Selection Between Proton and Photon Therapy in Thoracic Cancer. [PDF]

Cancers (Basel)
Zhu L, Yu NY, Tegtmeier RC, Ashman JB, Anand A, Duan J, Chen Q, Rong Y.   +7 more
europepmc   +1 more source

Delicate Management of Alkaline‐Substrate‐Induced Interfacial Reactions Enables High‐Efficiency and Stable Deep‐Red CsPbI3 Perovskite Light‐Emitting Diodes

Advanced Science, EarlyView.
We develop a magnesium‐doping strategy to delicately modulate the alkaline substrate‐induced reactions, ensuring high‐quality CsPbI3 perovskite emissive layers with substantially improved stability. The resultant deep‐red LEDs demonstrate a high peak external quantum efficiency of 23.62% and an exceptional half‐lifetime stability of 376 h at 20 mA cm−2,
Zhennan Tian, Jun Wu, Haifeng Zhao, Yong Yang, Zexi Chen, Tianxiang Lv, Xuehang Chen, Lei Yang, Ding Zheng, Chunyang Yin, Junsheng Yu, Sai Bai   +11 more
wiley   +1 more source

Radiotherapy quality assurance in the PROTECT trial - a European randomised phase III-trial comparing proton and photon therapy in the treatment of patients with oesophageal cancer. [PDF]

Acta Oncol
Skinnerup Byskov C, Mortensen HR, Biston MC, Broggi S, Bütof R, Canters R, Crehange G, Defraene G, Doyen J, Ehmsen ML, Fabiano S, Fracchiola F, Goudjil F, Haustermans K, Jensen SE, Jensen MF, Lecornu M, Makocki S, Mana AL, Martignano A, Meijers A, Mirandola A, Mitrea DA, Muijs CT, Møller DS, Nordsmark M, Orlandi E, Balermpas P, Populaire P, Scartoni D, Serrand J, Shamshad M, Slim N, Vanoni V, Vela A, Vidal M, Vilches-Freixas G, Weber D, Hoffmann L.   +38 more
europepmc   +1 more source

Engineering Ultrastable Intrinsic Radicals: Graphene Quantum Dots With NIR‐II Emission for Dynamic Deep‐Tissue Bioimaging

Advanced Science, EarlyView.
Stable radicals are attractive for photonic and quantum information technologies but are often limited by instability. We stabilize intrinsic radicals in graphene quantum dots via 2D polymerization of perylene derivatives, where bilayer defect confinement suppresses quenching (100–500 K).
Qin Xu, Yijie Hou, Bingzhe Wang, Tesen Zhang, Yupeng Liu, Shuaiqi Li, Maohua Chen, Guichuan Xing, Dongbo Guo, Songnan Qu   +9 more
wiley   +1 more source

Differences in Patterns of Care and Referral Between Proton and Photon Therapy. [PDF]

Int J Part Ther
Hasan S, Verma V, Abel S, Wegner RE, Choi JI, Press RH, Chhabra A, Simone CB.   +7 more
europepmc   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

Comparison of proton therapy and photon therapy for early-stage non-small cell lung cancer: a meta-analysis. [PDF]

Biomark Res
He J, Liu Y, Zhang X, Li B, Yang L, Wang H, Wang S, Yu J, Wang L.   +8 more
europepmc   +1 more source

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

A radiation therapy platform to enable upright cone beam computed tomography and future upright treatment on existing photon therapy machines. [PDF]

Med Phys
Korte JC, Wright M, Krishnan PG, Winterling N, Rahim S, Woodford K, Pearson E, Harden S, Hegi-Johnson F, Plumridge N, Fua T, Moodie K, Fielding A, Hegarty S, Kron T, Hardcastle N.   +15 more
europepmc   +1 more source