A New Proton Therapy Solution Provides Superior Cardiac Sparing Compared With Photon Therapy in Whole Lung Irradiation for Pediatric Tumor Patients. [PDF]
Sha X +8 more
europepmc +1 more source
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley +1 more source
Piezo‐Coupling Effects in Smart Polymers: Toward Ultrasensitive Sensing and Biomedical Applications
Piezo‐coupling effects are the foundational factors for the development of multifunctional and self‐powered platforms. Central to this advancement is the use of stimuli‐responsive smart polymers, which offer mechanical flexibility, biocompatibility, and simplified structural complexity with improved sensitivity and energy efficiency.
Duc Khanh Tran +6 more
wiley +1 more source
From Sourcing to End‐of‐Life: Sustainability Challenges and Opportunities in Organic Bioelectronics
Organic bioelectronics bridges biology and electronics using organic mixed ionic/electronic conductors. This Perspective addresses sustainability across the full lifecycle of organic bioelectronic materials and devices, offering a framework to guide material sourcing, synthesis, fabrication, application, and end‐of‐life strategies toward bioelectronic ...
Gwennaël Dufil +3 more
wiley +1 more source
Assessment of robustness against setup uncertainties using probabilistic scenarios in lung cancer: a comparison of proton with photon therapy. [PDF]
Teoh S +4 more
europepmc +1 more source
The PS‐QRC nanoprobe employs L‐serine as a targeting ligand for kidney injury molecule‐1 (KIM‐1) to achieve accumulation in injured renal tissues. Upon activation by reactive oxygen species (ROS), it undergoes a self‐amplifying cascade to release fluorophores for near‐infrared fluorescence (NIRF) imaging, enabling ultra‐early diagnosis of acute kidney ...
Yahui Chen +10 more
wiley +1 more source
Impact of Rectal Spacer on Toxicity Reduction in Men Treated With Proton Versus Photon Therapy. [PDF]
Dhere VR +11 more
europepmc +1 more source
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang +12 more
wiley +1 more source
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang +18 more
wiley +1 more source
Influence of Target Location, Size, and Patient Age on Normal Tissue Sparing- Proton and Photon Therapy in Paediatric Brain Tumour Patient-Specific Approach. [PDF]
Dell'Oro M +6 more
europepmc +1 more source

