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Two-Photon Photodynamic Therapy

Journal of Clinical Laser Medicine & Surgery, 1997
We demonstrate the use of infrared excitation in conjunction with an efficient two-photon absorbing dye and a photosensitizer in photodynamic therapy.An efficient two-photon absorbing dye is excited by short infrared (800 nm) laser pulses, which transfer its energy to the photosensitizer and the photosensitizer, in turn, generates the singlet oxygen.A ...
J D, Bhawalkar   +3 more
openaire   +2 more sources

Biological Considerations When Comparing Proton Therapy With Photon Therapy

Seminars in Radiation Oncology, 2013
Owing to the limited availability of data on the outcome of proton therapy, treatments are generally optimized based on broadly available data on photon-based treatments. However, the microscopic pattern of energy deposition of protons differs from that of photons, leading to a different biological effect.
Paganetti, Harald, van Luijk, Peter
openaire   +2 more sources

Motion in radiotherapy: photon therapy

Physics in Medicine and Biology, 2012
This review considers the management of motion in photon radiation therapy. An overview is given of magnitudes and variability of motion of various structures and organs, and how the motion affects images by producing artifacts and blurring. Imaging of motion is described, including 4DCT and 4DPET.
openaire   +3 more sources

On bolus for megavoltage photon and electron radiation therapy

Medical Dosimetry, 2013
Frequently, in radiation therapy one must treat superficial lesions on cancer patients; these are at or adjacent to the skin. Megavoltage photon radiotherapy penetrates through the skin to irradiate deep-seated tumors, with skin-sparing property. Hence, to treat superficial lesions, one must use a layer of scattering material to feign as the skin ...
Vedang, Vyas   +7 more
openaire   +2 more sources

Optimization of photon beam flatness for radiation therapy

Physics in Medicine and Biology, 2007
In this work, we investigate the relation between lateral fluence/dose distributions and photon beam uniformity, possibly identifying ways to improve these characteristics. The calculations included treatment head scatter properties associated with three common types of linear accelerators in order to study their impact on the results.
Jörgen, Olofsson   +3 more
openaire   +2 more sources

Regenerative photonic therapy: Review

AIP Conference Proceedings, 2012
After four decades of research of photobiomodulation phenomena in mammals in vitro and in vivo, a solid foundation is created for the use of photobiomodulation in regenerative medicine. Significant accomplishments are achieved in animal models that demonstrate opportunities for photo-regeneration of injured or pathological tissues: skin, muscles and ...
Natasha Salansky, Norman Salansky
openaire   +1 more source

Exit dose studies in megavoltage photon therapy

The British Journal of Radiology, 1983
A coin-shaped ionisation chamber, orientated with its thin window facing away from the radiation source, was used to investigate the dose perturbations caused by the absence of back-scattering material near the exit surface of solid phantoms. Cobalt 60 and 4, 8 and 16 MV X-ray beams were used in the study. With no scattering material beyond the chamber
G D, Lambert   +3 more
openaire   +2 more sources

Collimator scatter in photon therapy beams

Medical Physics, 1995
A model for collimator photon scatter calculations is presented. The scatter from a collimating block is separated into two categories, one being the scatter released from photons entering the block through the surface facing the source, and one from photons striking the block tangentially through the side tangential to the beam.
openaire   +2 more sources

Photon and photon–neutron experimental dosimetry in Grid therapy with 18 MV photon beams

Journal of Radiotherapy in Practice, 2020
AbstractPropose:Spatially fractionated Grid radiation therapy (SFGRT) in an effective technique for bulky and radio-sensitive tumours. SFGRT using a constructed block has been used to evaluate the photon and photo-neutron (PN) dose measurement in 18-MV photon beam energy.Methods and materials:A mounted Grid block on to a Varian Clinac 2100c linear ...
Sareh Tajiki   +6 more
openaire   +1 more source

Two-photon excitation nanoparticles for photodynamic therapy

Chemical Society Reviews, 2016
Integration of the two-photon excitation (TPE) technique and nanomaterials to construct TPE nanoparticle-based photosensitizers for PDT is summarized and reviewed.
Yizhong, Shen   +4 more
openaire   +2 more sources

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