Results 41 to 50 of about 2,714,943 (294)

Proton therapy of a pregnant patient with nasopharyngeal carcinoma

Clinical and Translational Radiation Oncology, 2022
Background and purpose: Radiotherapy during pregnancy is rarely administered due to lack of data and practical challenges. This is the first detailed report of proton therapy as cancer treatment for a pregnant patient with nasopharyngeal carcinoma ...
Joosje H. Heimovaara, Jeroen Blommaert, Jeffrey Free, René A. Bolt, Elske M. Gort, Tom Depuydt, Cristina Boso Martinez, Mirthe H. Schoots, Mathilde van Gerwen, Marry van den Heuvel-Eibrink, Johannes A. Langendijk, Carolien P. Schröder, Frédéric Amant, Sanne J. Gordijn, Edwin Oldehinkel   +14 more
doaj   +1 more source

Fast Monte Carlo Simulation of ⁹⁰Y Bremsstrahlung using a Kernel-based Photon Source [PDF]

, 2011
In targeted radionuclide therapy using ⁹⁰Y, bremsstrahlung photons can be used for imaging and subsequently for absorbed dose estimation. Monte Carlo simulation is a reliable method to study bremsstrahlung imaging but it takes a long computation time as ...
Zakariah, Suhaili
core  

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

A systematic literature review: deep learning techniques for synthetic medical image generation and their applications in radiotherapy

Frontiers in Radiology
The aim of this systematic review is to determine whether Deep Learning (DL) algorithms can provide a clinically feasible alternative to classic algorithms for synthetic Computer Tomography (sCT).
Moiz Khan Sherwani, Shyam Gopalakrishnan
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Feasibility study for proton dose calculation of esophageal squamous cell carcinoma based on stopping power ratio directly derived from dual energy CT

Frontiers in Oncology
PurposeTo investigate the feasibility of proton therapy planning using stopping power ratio (SPR) maps directly generated from spectral CT raw data, and to perform a comparative evaluation of dose calculation uncertainties between SPR maps derived from ...
Miaomiao Li, Miaomiao Li, Yongbin Cui, Xinjun Lin, Yuanyuan Yan, Qianyu Liu, Mingming Nie, Wenzhen Gong Ye, Yong Huang, Jinhu Chen, Yong Yin   +10 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Combined carbon photon and hydrogel therapy mediates the synergistic repair of full-thickness skin wounds

Journal of International Medical Research, 2020
Objective This study investigated the synergistic repair effects of Prontosan hydrogel and carbon photon therapy in a rat full-thickness wound model. Methods The wavelength distribution of the photon source was determined.
Fan Yang, Xiuling Zhou, Sitong Chen, Qiuju Li, Ronghang Li, Chunying Li, Chenyu Shi, Lanyu Zhu   +7 more
doaj   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Two-photon interference at telecom wavelengths for time-bin-encoded single photons from quantum-dot spin qubits [PDF]

, 2015
This work was supported by the JST through its ImPACT Program, NICT, NSF CCR-08 29694, NIST 60NANB9D9170, Special Coordination Funds for Promoting Science and Technology, and the State of Bavaria. C.L. and M.M.F. acknowledge support through the AFOSR.
Natarajan, Chandra M., Yu, Leo, Horikiri, Tomoyuki, Pelc, Jason S., Höfling, Sven, Hadfield, Robert H, Langrock, Carsten, Maier, Sebastian, Natarajan , Chandra M., Fejer, Martin M., Schneider, Christian, Hadfield, Robert H., Tanner, Michael G.; id_orcid, Tanner, Michael G., Abe, Eisuke, Kamp, Martin, Yamamoto, Yoshihisa   +16 more
core   +1 more source