Results 41 to 50 of about 158,771 (296)

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

Combined carbon photon and hydrogel therapy mediates the synergistic repair of full-thickness skin wounds

Journal of International Medical Research, 2020
Objective This study investigated the synergistic repair effects of Prontosan hydrogel and carbon photon therapy in a rat full-thickness wound model. Methods The wavelength distribution of the photon source was determined.
Fan Yang, Xiuling Zhou, Sitong Chen, Qiuju Li, Ronghang Li, Chunying Li, Chenyu Shi, Lanyu Zhu   +7 more
doaj   +1 more source

Comparative evaluation of a novel, moderately hypofractionated radiation protocol in 56 dogs with symptomatic intracranial neoplasia [PDF]

, 2018
BACKGROUND: Use of strongly hypofractionated radiation treatments in dogs with intracranial neoplasia did not improve outcomes and yielded increased rates of toxicosis.
Bentley, Bhatti, Brearley, Gladwish, Griffin, Hansen, International Commission on Radiation Units and Measurements, International Commission on Radiation Units and Measurements, International Commission on Radiation Units and Measurements, Kent, Keyerleber, Keyerleber, Ladue, Lawrence, Lipsitz, Macdonald, Marcinowska, Rock, Rodenas, Rohrer Bley, Rohrer Bley, Rohrer Bley, Rohrer Bley, Ruben, Stockham, Theon, Thomson, Treggiari, Turrel, Wolff, Young, Zwingenberger   +31 more
core   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Coupled Photon and Heat Transport Simulation inside Biological Tissue for Laser Therapy

Journal of Thermal Science and Technology, 2009
The objective of this study is to develop a new simulator for laser therapy. In order to minimize undesired effects on the laser therapy, it is important to precisely predict for heat and photon transport inside a biological tissue. In the present study,
Atsushi SAKURAI, Isami NITTA, Shigenao MARUYAMA, Junnosuke OKAJIMA, Koji MATSUBARA   +4 more
doaj   +1 more source

Does radiation therapy need more than two photon energies from Linac?

Frontiers in Oncology, 2022
PurposeModern Linacs are equipped with multiple photon energies for radiation therapy, and proper energy is chosen for each case based on tumor characteristics and patient anatomy.
Xile Zhang, Xile Zhang, Fugen Zhou, Fugen Zhou, Bo Liu, Bo Liu, Tianyu Xiong, Xiangzhi Bai, Xiangzhi Bai, Qiuwen Wu   +9 more
doaj   +1 more source

Cost-comparativeness of proton versus photon therapy

Chinese Clinical Oncology, 2016
Proton beam radiotherapy (PBT) offers great promise in the treatment of a wide variety of cancers owing to the sharp drop-off in radiation dose at a defined point, known as the Bragg peak, beyond which there is no appreciable dose. However, it is also well-understood that PBT is associated with large economic costs, including both capital investment ...
Vivek, Verma, Chirag, Shah, Jean-Claude M, Rwigema, Timothy, Solberg, Xiaofeng, Zhu, Charles B, Simone   +5 more
openaire   +2 more sources

CT number calibration audit in photon radiation therapy

Medical Physics, 2023
AbstractBackgroundInadequate computed tomography (CT) number calibration curves affect dose calculation accuracy. Although CT number calibration curves registered in treatment planning systems (TPSs) should be consistent with human tissues, it is unclear whether adequate CT number calibration is performed because CT number calibration curves have not ...
Minoru, Nakao, Shuichi, Ozawa, Hideharu, Miura, Kiyoshi, Yamada, Masahiro, Hayata, Kosuke, Hayashi, Daisuke, Kawahara, Takeo, Nakashima, Yusuke, Ochi, Takuro, Okumura, Haruhide, Kunimoto, Atsushi, Kawakubo, Hayate, Kusaba, Hiroshige, Nozaki, Kosaku, Habara, Naoki, Tohyama, Teiji, Nishio, Mitsuhiro, Nakamura, Toshiyuki, Minemura, Hiroyuki, Okamoto, Masayori, Ishikawa, Masahiko, Kurooka, Hidetoshi, Shimizu, Kenji, Hotta, Masahide, Saito, Masahiro, Nakano, Masato, Tsuneda, Yasushi, Nagata   +27 more
openaire   +2 more sources