Results 191 to 200 of about 62,604 (264)
Cilia in Nervous System Development, Function, and Disease
MedComm – Future Medicine, Volume 5, Issue 2, June 2026.Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley +1 more source
Identification of Genes Required for Apical Protein Trafficking in Drosophila Photoreceptor Cells. [PDF]
G3 (Bethesda), 2019 Laffafian A, Tepass U.
europepmc +1 more source
The Journal of Pathology, Volume 269, Issue 2, Page 222-231, June 2026.Abstract MYO7A is a causal gene, underlying Usher syndrome type 1B (USH1B) and both autosomal recessive (DFNB2) and dominant (DFNA11) non‐syndromic hearing loss. Despite the large number of reported MYO7A variants (over 2,200), variants located in an extended splice region remain difficult to interpret and are often classified as variants of uncertain ...
Tao Shi +5 more
wiley +1 more source
Expression and significance of miR - 20b in retinal photoreceptor cells exposed to PCB1254. [PDF]
Aging (Albany NY), 2019 Zhang X +7 more
europepmc +1 more source
Smart Medicine, Volume 5, Issue 3, June 2026.Magnetic fields modulate macrophage‐cancer crosstalk through the STING‐TRPC1 axis. Exposure reprograms macrophages toward the anti‐cancer phenotype. Exposing cancer cells modulates cancer secretome to promote polarization and selective recruitment of M1‐tumoricidal macrophages, enhancing cancer immunogenicity.
Viresh Krishnan Sukumar +7 more
wiley +1 more source
Aging Cell, Volume 25, Issue 6, June 2026.The molecular mechanisms of RORA targeting PRNP activate oxidative injury‐induced cellular senescence and apoptosis of lens epithelial cells. Current research confirms that the transcription factor RORA targets PRNP, exacerbating cellular senescence and apoptosis of LECs (Figure 7).
Yue Zou +11 more
wiley +1 more source
Vitreoretinal complications and surgical outcomes in patients with X‐linked retinoschisis
Acta Ophthalmologica, Volume 104, Issue 4, Page 410-422, June 2026.Abstract Purpose X‐linked retinoschisis (XLRS) is an inherited vitreoretinal disorder characterized by macular retinoschisis. In a subgroup of patients, peripheral retinoschisis can occur, potentially leading to complications such as vitreous haemorrhage (VH) and retinal detachment (RD).
Jonathan Hensman +11 more
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GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling
British Journal of Pharmacology, Volume 183, Issue 11, Page 2619-2633, June 2026.G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
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Cell Proliferation, Volume 59, Issue 6, June 2026.The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao +6 more
wiley +1 more source
Cell Proliferation, Volume 59, Issue 6, June 2026.Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang +8 more
wiley +1 more source