Cell Reports, 2020 Summary: Otx family homeoproteins Otx2 and Crx are expressed in photoreceptor precursor cells and bind to the common DNA-binding consensus sequence, but these two proteins have distinct functions in retinal development.
Haruka Yamamoto +2 more
exaly +3 more sources
Light-modulated stem cells in the camera-type eye of an annelid model for adult brain plasticity [PDF]
Nature CommunicationsCamera-type eyes in vertebrates and cephalopods are striking examples of parallel evolution of a complex structure. While comparisons have focused on these two groups, camera-type eyes with likely high functionality are also found in other invertebrate ...
Nadja Milivojev +6 more
doaj +2 more sources
A Dynamic Change of Microglial States Occurs During the Transition From Photoreceptor Degeneration to Regeneration in Zebrafish pde6c Mutants. [PDF]
GliaZebrafish pde6c mutants undergo photoreceptor degeneration from 5 dpf, but rods regenerate from 4 wpf. scRNA‐seq of retinal microglia reveals dynamic change of states between 5 dpf and 4 wpf. Two states emerge specifically during regeneration. ABSTRACT Microglia, brain‐resident immune cells, maintain brain homeostasis.
Ravishankar D, Takeuchi Y, Masai I.
europepmc +2 more sources
Universality of Form: The Case of Retinal Cone Photoreceptor Mosaics
Entropy, 2023 Cone photoreceptor cells are wavelength-sensitive neurons in the retinas of vertebrate eyes and are responsible for color vision. The spatial distribution of these nerve cells is commonly referred to as the cone photoreceptor mosaic.
Alireza Beygi
doaj +1 more source
Activation of Transducin by Bistable Pigment Parapinopsin in the Pineal Organ of Lower Vertebrates. [PDF]
PLoS ONE, 2015 Pineal organs of lower vertebrates contain several kinds of photosensitive molecules, opsins that are suggested to be involved in different light-regulated physiological functions. We previously reported that parapinopsin is an ultraviolet (UV)-sensitive
Emi Kawano-Yamashita +5 more
doaj +1 more source
Extracellular vesicles highlight many cases of photoreceptor degeneration
Frontiers in Molecular Neuroscience, 2023 The release of extracellular vesicles is observed across numerous cell types and serves a range of biological functions including intercellular communication and waste disposal.
William J. Spencer
doaj +1 more source
BMC Biology, 2021 Background Pineal-related organs in cyclostomes, teleosts, amphibians, and reptiles exhibit color opponency, generating antagonistic neural responses to different wavelengths of light and thereby sensory information about its “color”.
Seiji Wada +5 more
doaj +1 more source
Histamine Recycling Is Mediated by CarT, a Carcinine Transporter in Drosophila Photoreceptors. [PDF]
PLoS Genetics, 2015 Histamine is an important chemical messenger that regulates multiple physiological processes in both vertebrate and invertebrate animals. Even so, how glial cells and neurons recycle histamine remains to be elucidated.
Ying Xu +5 more
doaj +1 more source
TULP4, a novel E3 ligase gene, participates in neuronal migration as a candidate in schizophrenia
CNS Neuroscience &Therapeutics, EarlyView., 2023 Mutations identified from four SCZ pedigrees resulted in decreased TULP4 expression. Tulp4 knockdown caused delayed neuron migration in embryonic mice, and impaired cognition and prepulse inhibition in adult mice. These phenotypes may be related to TULP4 through its involvement in the formation of a novel E3 ubiquitin ligases.
Yan Bi +19 more
wiley +1 more source
The Par-PrkC polarity complex is required for cilia growth in zebrafish photoreceptors. [PDF]
PLoS ONE, 2014 Specification and development of the apical membrane in epithelial cells requires the function of polarity proteins, including Pard3 and an atypical protein kinase C (PrkC). Many epithelial cells possess microtubule-based organelles, known as cilia, that
Bryan L Krock, Brian D Perkins
doaj +1 more source