Results 11 to 20 of about 4,900,943 (176)

Protein and signaling networks in vertebrate photoreceptor cells [PDF]

open access: yesFrontiers in Molecular Neuroscience, 2015
Vertebrate photoreceptor cells are exquisite light detectors operating under very dim and bright illumination. The photoexcitation and adaptation machinery in photoreceptor cells consists of protein complexes that can form highly ordered supramolecular ...
Karl-Wilhelm eKoch, Daniele eDell'Orco
doaj   +2 more sources

A Müller Glia‐Retinal Pigment Epithelium Apical Network Surrounding Cone Outer Segments in Fish and Mouse [PDF]

open access: yesGlia, Volume 74, Issue 12, December 2026.
Müller glia and the retinal pigment epithelium interact around cone outer segment in the subretinal space of both zebrafish and mouse. The contacts are established early during development but subsequent to outer segment emergence. ABSTRACT Homeostasis of the vertebrate retina critically depends on two non‐neuronal cell populations, Müller glia and the
Maria Sharkova   +6 more
wiley   +2 more sources

Patterns of Proliferation in the Pacific Hagfish (Eptatretus stoutii) Retina Suggest an Ancient Origin for Adult Neurogenesis [PDF]

open access: yesJournal of Comparative Neurology, Volume 534, Issue 10, October 2026.
The hagfish, a jawless early‐branching vertebrate, has very rudimentary eyes that are diminutive and oddly devoid of melanin pigment. Yet, the degenerate hagfish eye grows throughout life and expresses canonical genes of vertebrate retinal development. ABSTRACT Comparative morphology has revealed fascinating structural and organizational differences in
Sarah N. Bradshaw, William T. Allison
wiley   +2 more sources

Lrit1, a Retinal Transmembrane Protein, Regulates Selective Synapse Formation in Cone Photoreceptor Cells and Visual Acuity

open access: yesCell Reports, 2018
Summary: In the vertebrate retina, cone photoreceptors play crucial roles in photopic vision by transmitting light-evoked signals to ON- and/or OFF-bipolar cells.
Akiko Ueno   +12 more
doaj   +2 more sources

The Musashi 1 Controls the Splicing of Photoreceptor-Specific Exons in the Vertebrate Retina. [PDF]

open access: yesPLoS Genetics, 2016
Alternative pre-mRNA splicing expands the coding capacity of eukaryotic genomes, potentially enabling a limited number of genes to govern the development of complex anatomical structures.
Daniel Murphy   +4 more
doaj   +3 more sources

Monoaminergic modulation of photoreception in ascidian: evidence for a proto-hypothalamo-retinal territory [PDF]

open access: yesBMC Biology, 2012
Background The retina of craniates/vertebrates has been proposed to derive from a photoreceptor prosencephalic territory in ancestral chordates, but the evolutionary origin of the different cell types making the retina is disputed.
Razy-Krajka Florian   +7 more
doaj   +2 more sources

Functional analysis of Samd11, a retinal photoreceptor PRC1 component, in establishing rod photoreceptor identity

open access: yesScientific Reports, 2021
Establishing correct neuronal cell identity is essential to build intricate neural tissue architecture and acquire precise neural function during vertebrate development.
Shun Kubo   +6 more
doaj   +1 more source

A cell atlas of the chick retina based on single-cell transcriptomics

open access: yeseLife, 2021
Retinal structure and function have been studied in many vertebrate orders, but molecular characterization has been largely confined to mammals. We used single-cell RNA sequencing (scRNA-seq) to generate a cell atlas of the chick retina.
Masahito Yamagata   +2 more
doaj   +1 more source

Ancient multiplicity in cyclic nucleotide-gated (CNG) cation channel repertoire was reduced in the ancestor of Olfactores before re-expansion by whole genome duplications in vertebrates.

open access: yesPLoS ONE, 2022
Cyclic nucleotide-gated (CNG) cation channels are important heterotetrameric proteins in the retina, with different subunit composition in cone and rod photoreceptor cells: three CNGA3 and one CNGB3 in cones and three CNGA1 and one CNGB1 in rods.
David Lagman   +3 more
doaj   +1 more source

Notch pathway mutants do not equivalently perturb mouse embryonic retinal development.

open access: yesPLoS Genetics, 2023
In the vertebrate eye, Notch ligands, receptors, and ternary complex components determine the destiny of retinal progenitor cells in part by regulating Hes effector gene activity. There are multiple paralogues for nearly every node in this pathway, which
Bernadett Bosze   +4 more
doaj   +1 more source

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