Results 231 to 240 of about 64,303 (289)
Structure and function of the interphotoreceptor matrix surrounding retinal photoreceptor cells
, 2015 Makoto Ishikawa +2 more
openalex +1 more source
A Novel N‐Terminal PRPF6 Variant in Autosomal Dominant Retinitis Pigmentosa
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT This report identifies the first N‐terminal PRPF6 variant (c.514C>T) as a cause of autosomal dominant Retinitis Pigmentosa. This novel variant is associated with progressive peripheral vision loss but notably preserved central visual acuity, suggesting a distinct phenotypic expression compared to C‐terminal variants.
Na Li, Yalong Dang
wiley +1 more source
Photoreceptor cells as a source of fundus autofluorescence in recessive Stargardt disease. [PDF]
J Neurosci Res, 2019 Paavo M +4 more
europepmc +1 more source
Glia Regulate the Timing of Photoreceptor Differentiation in the Drosophila Visual System
Glia, Volume 74, Issue 2, February 2026.Activation of EGFR signaling in sub‐retinal glia is required for timing photoreceptor differentiation in the Drosophila visual system. ILP3 and ILP6 are downstream targets of the EGFR pathway in sub‐retinal glia, which activate insulin signaling in photoreceptor precursor cells in the developing retina.
Qian Ren, Wen‐Tzu Chang, Yong Rao
wiley +1 more source
Deceptive beauty of non‐natural structures
Protein Science, Volume 35, Issue 2, February 2026.Abstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Vsevolod V. Gurevich +1 more
wiley +1 more source
Aging Cell, Volume 25, Issue 2, February 2026.MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong +9 more
wiley +1 more source
Acta Ophthalmologica, Volume 104, Issue 1, Page 89-97, February 2026.Abstract Purpose To evaluate test–retest variability (TRV) of the full‐field stimulus test (FST) in patients with retinitis pigmentosa (RP) and poor best‐corrected visual acuity (BCVA; ≤20/50 Snellen; ≥0.40 logMAR), and to assess the reliability of FST as a clinical endpoint in future RP trials.
J. S. Karuntu +2 more
wiley +1 more source
Unilateral optic neuritis and thinning of retinal layers in the affected and unaffected eyes
Acta Ophthalmologica, Volume 104, Issue 1, Page e84-e94, February 2026.Abstract Purpose Multiple sclerosis (MS)‐related optic neuritis (ON) causes thinning of inner retinal layers. It remains unclear whether unilateral MSON also affects the unaffected contralateral eye. The purpose of this study was to compare macular retinal layer thicknesses in MS eyes with unilateral optic neuritis (MSON), their unaffected ...
Sanna Leinonen +4 more
wiley +1 more source