Results 221 to 230 of about 62,604 (264)
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Vertebrate photoreceptor cell development and disease
Trends in Cell Biology, 1998Photoreceptors provide an excellent model for studies of vertebrate neuronal differentiation, and many human diseases resulting in blindness primarily affect photoreceptors. There is therefore great interest in studying the cellular and molecular mechanisms of photoreceptor development.
E M, Morrow, T, Furukawa, C L, Cepko
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The Biochemistry of Photoreceptor Cells
1981Photoreceptor cells have high rates of metabolism, and enzyme distributions suggest considerable substrate movement. We have used tracer techniques to study the effects of light on photoreceptor metabolism. In vitro, glutamine is metabolized alongside glucose by rat photoreceptors, and is, potentially, a major precursor of the neuroactive amino acids ...
M. J. Voaden +2 more
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TRP, TRPL and trouble in photoreceptor cells
Current Opinion in Neurobiology, 1998Calcium influx through the TRP and TRPL light-activated channels triggers a complex regulatory hierarchy resulting in positive and negative feedback regulation of the phototransduction cascade. Recent studies have begun to elucidate the function of TRP and TRPL in vivo, and to examine their relationship to intracellular calcium changes during the light
K, Scott, C, Zuker
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Ca2+ Signaling in Drosophila Photoreceptor Cells
2019In Drosophila photoreceptor cells, Ca2+ exerts regulatory functions that control the shape, duration, and amplitude of the light response. Ca2+ also orchestrates light adaptation allowing Drosophila to see in light intensity regimes that span several orders of magnitude ranging from single photons to bright sunlight. The prime source for Ca2+ elevation
Olaf, Voolstra, Armin, Huber
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Calcium Homeostasis in Fly Photoreceptor Cells
2002In fly photoreceptor cells, two processes dominate the Ca2+ homeostasis: light-induced Ca2+ influx through members of the TRP family of ion channels, and Ca2+ extrusion by Na+/Ca2+ exchange. Ca2+ release from intracellular stores is quantitatively insignificant.
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Peroxynitrite-induced apoptosis in photoreceptor cells
Current Eye Research, 2004To study the mechanisms of peroxynitrite-induced photoreceptor cell damage, using retinal cultures and a peroxynitrite donor, 3-morpholinosydnonimine (SIN-1).Retinal explants obtained from 20-day-old Lewis rat pups, were exposed to SIN-1 for varying lengths of time at varying concentrations.
Shinji, Ito +5 more
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Evolution of eyes and photoreceptor cell types
The International Journal of Developmental Biology, 2003The evolution of the eye is a matter of debate ever since Darwin's Origin of Species. While morphological comparisons of eye anatomy and photoreceptor cell types led to the view that animal eyes evolved multiple times independently, the molecular conservation of the pax6 eye-specifying cascade has indicated the contrary - that animal eyes evolved from ...
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Properties of barnacle photoreceptor cells in culture
Comparative Biochemistry and Physiology Part A: Physiology, 19891. Properties of median photoreceptor cells in cultured ocelli from the giant barnacle (Balanus nubilus) were compared in isolated ocelli, ocelli maintained with the supraesophageal ganglion, and fresh ocelli. 2. Cultured photoreceptor cells exhibited slight deterioration after 2-4 weeks.
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The dynamics of cytosolic calcium in photoreceptor cells
BioEssays, 1995AbstractAnalysis of the lightâinduced changes of cytosolic Ca2+ ([Ca2+]i) in photoreceptor cells has been taken a step further with two recently published studies(1,2). In one, changes in [Ca2+]i were measured in single detached rod outer segments from Gecko in response to various light intensities.
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Strategies for rescue of retinal photoreceptor cells
Current Opinion in Neurobiology, 1993A variety of genetic and environmental factors cause degeneration of retinal photoreceptors. This review focuses on current strategies to rescue defective, but still viable, rods and cones, including transplantation of normal retinal pigment epithelium cells, corrective gene therapy, administration of survival/growth factors, protection from the ...
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