Results 91 to 100 of about 108,777 (309)

Case Report: Solar retinopathy following exposure to reflected sunlight

Journal of Ophthalmology, 2019
Background: Radiation damage to the eye is most commonly caused by sunlight. Solar retinopathy is a form of retinal damage that occurs after exposure to solar radiation, with the most common symptoms being reduced vision and central scotoma.
A.S. Krivoruchko, K.G. Drachenko, S.K. Drachenko, A.R. Korol   +3 more
doaj   +1 more source

Tree shrew model of early diabetic retinopathy reveals microvascular dysfunction and identifies phosphoserine aminotransferase 1 as a novel therapeutic target

Animal Models and Experimental Medicine, EarlyView.
We developed an animal model of early diabetic retinopathy (DR) in the tree shrew by feeding a high‐fat and high‐sugar diet in combination with STZ. Physiological and biochemical index detection, hematoxylin and eosin staining, and transmission electron microscopy were performed to examine DR.
Min Qiu, Shurui Huo, Wenguang Wang, Na Li, Qingwei Zeng, Xiaomei Sun, Jiejie Dai, Pinfen Tong, Yuanyuan Han, Ling Zhao, Caixia Lu   +10 more
wiley   +1 more source

Age-related deterioration of rod vision in mice [PDF]

, 2010
Even in healthy individuals, aging leads to deterioration in visual acuity, contrast sensitivity, visual field, and dark adaptation. Little is known about the neural mechanisms that drive the age-related changes of the retina and, more specifically ...
Crouch, Rosalie K, Fan, Jie, Kefalov, Vladimir J, Kolesnikov, Alexander V   +3 more
core   +2 more sources

Time‐Resolved Native Mass Spectrometry Reveals Reversible Light‐Driven Oligomerization of Arabidopsis Cryptochrome 1 and Its Antagonism by BIC1

Angewandte Chemie International Edition, EarlyView.
Time‐resolved native mass spectrometry uncovers the blue‐light‐dependent kinetic mechanism of Arabidopsis CRY1 oligomerization, proceeding sequentially from monomers to dimers and tetramers. ATP promotes assembly, whereas BIC1 actively blocks and disassembles tetramers independent of light, providing mechanistic insight into the regulation of ...
Alicia Just, Nils Niemann, Petra Gnau, Dennis Kock, Thomas Heimerl, Stephan Kiontke, Lars‐Oliver Essen, Alfred Batschauer, Nina Morgner   +8 more
wiley   +1 more source

Morphology and connectivity of retinal horizontal cells in two avian species

Frontiers in Cellular Neuroscience
In the outer vertebrate retina, the visual signal is separated into intensity and wavelength information. In birds, seven types of photoreceptors (one rod, four single cones, and two members of the double cone) mediate signals to >20 types of second ...
Anja Günther, Vaishnavi Balaji, Bo Leberecht, Julia J. Forst, Alexander Y. Rotov, Tobias Woldt, Dinora Abdulazhanova, Henrik Mouritsen, Henrik Mouritsen, Karin Dedek, Karin Dedek   +10 more
doaj   +1 more source

Random Photon Absorption Model Elucidates How Early Gain Control in Fly Photoreceptors Arises from Quantal Sampling [PDF]

, 2016
Many diurnal photoreceptors encode vast real-world light changes effectively, but how this performance originates from photon sampling is unclear. A 4-module biophysically-realistic fly photoreceptor model, in which information capture is limited by the ...
Bevington, Boschek, Dodge, Frolov, Fuortes, Gonzalez-Bellido, Hardie, Hecht, Henderson, Hochstrate, Howard, Juusola, Juusola, Juusola, Laughlin, Mikko Juusola, Pugh, Pumir, Rushton, Sjostrand, Song, Song, Stavenga, Van Hateren, Vogt, Warrant, Wu, Wu, Yu Zhou, Zhuoyi Song   +29 more
core   +1 more source

Clock genes regulate Ca2+ signaling and mitochondrial bioenergetics to inhibit Sjogren's disease

Arthritis &Rheumatology, Accepted Article.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjogren's disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA seq, and mitochondrial activity were used to investigate the effects of ...
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento Da Conceicao, Neelanjan Vishnu, Shankara N Varadarajan, Venugopal R. Bovilla, Rajender K Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Calcium-sensor proteins but not bicarbonate ion activate retinal photoreceptor membrane guanylyl cyclase in photoreceptors

Frontiers in Molecular Neuroscience
Retinal membrane guanylyl cyclase (RetGC), regulated by guanylyl cyclase activating proteins (GCAPs) via negative calcium-feedback, is one of the most critically important enzymes in vertebrate rod and cone physiology, enabling their sensitivity to light.
Igor V. Peshenko, Elena V. Olshevskaya, Alexander M. Dizhoor, Alexander M. Dizhoor   +3 more
doaj   +1 more source

Light‐Induced Anion Translocation to Control Helical Folding in an Artificial Communication System

Chemistry – A European Journal, EarlyView.
Anion‐induced helical folding of an oligomer is controlled indirectly and reversibly by light through anion uptake/release by a photoresponsive receptor. Thus, a light signal is processed into a chemical signal in a communication‐type three‐component supramolecular system.
Indigo M. Bekaert, Suchismita Saha, Julia Villalva, David Villarón, Maxime A. Siegler, Sander J. Wezenberg   +5 more
wiley   +1 more source

Comprehensive study of SNAREs involved in the post-Golgi transport in Drosophila photoreceptors

Frontiers in Cell and Developmental Biology
Polarized transport is essential for the construction of multiple plasma membrane domains within cells. Drosophila photoreceptors serve as excellent model systems for studying the mechanisms of polarized transport.
Yuka Ochi, Hitomi Yamashita, Shogo Sasaki, Takumi Ogawa, Yumi Yamada, Tatsuya Tago, Takunori Satoh, Akiko K. Satoh   +7 more
doaj   +1 more source