Results 51 to 60 of about 13,653 (246)

Targeted photoredox catalysis in cancer cells [PDF]

Nature Chemistry, 2019
Hypoxic tumours are a major problem for cancer photodynamic therapy. Here, we show that photoredox catalysis can provide an oxygen-independent mechanism of action to combat this problem. We have designed a highly oxidative Ir(III) photocatalyst, [Ir(ttpy)(pq)Cl]PF6 ([1]PF6, where 'ttpy' represents 4'-(p-tolyl)-2,2':6',2''-terpyridine and 'pq ...
Huang, Huaiyi, Banerjee, Samya, Qiu, Kangqiang, Zhang, Pingyu, Blacque, Olivier, Malcomson, Thomas, Paterson, Martin J, Clarkson, Guy J, Staniforth, Michael, Stavros, Vasilios G, Gasser, Gilles, Chao, Hui, Sadler, Peter J   +12 more
openaire   +4 more sources

Convergent Total Synthesis of 16β‐Hydroxylpseudobufarenogin

Angewandte Chemie, EarlyView.
We present a novel convergent strategy that integrates Pd/Ag‐promoted Suzuki–Miyaura coupling with Ir‐catalyzed radical‐relay cyclization, enabling the first total synthesis of 16β‐hydroxylpseudobufarenogin. This approach is broadly applicable to the total synthesis of various oxygenated bufadienolides by simply modifying the fragment structures ...
Wataru Shigematsu, Yo Matsumoto, Koichi Hagiwara, Masayuki Inoue   +3 more
wiley   +2 more sources

Recent developments in photoredox-catalyzed remote ortho and para C–H bond functionalizations

Beilstein Journal of Organic Chemistry, 2020
In recent years, the research area of direct C–H bond functionalizations was growing exponentially not only due to the ubiquity of inert C–H bonds in diverse organic compounds, including bioactive natural and nonnatural products, but also due to its ...
Rafia Siddiqui, Rashid Ali
doaj   +1 more source

Excited Organic Radicals in Photoredox Catalysis. [PDF]

JACS Au
Many important synthetic-oriented works have proposed excited organic radicals as photoactive species, yet mechanistic studies raised doubts about whether they can truly function as photocatalysts. This skepticism originates from the formation of (photo)redox-active degradation products and the picosecond decay of electronically excited radicals, which
Pfund B, Wenger OS.
europepmc   +4 more sources

Enantioselective Decarboxylative Arylation of α-Amino Acids via the Merger of Photoredox and Nickel Catalysis [PDF]

, 2016
An asymmetric decarboxylative C_(sp)^3–C_(sp)^2 cross-coupling has been achieved via the synergistic merger of photoredox and nickel catalysis. This mild, operationally simple protocol transforms a wide variety of naturally abundant α-amino acids and ...
David W. C. MacMillan, Gregory C. Fu, Huan Cong, Junwon Choi, Lane R. M., Lawrence S. A., Nugent T. C., Wei Li, Zhiwei Zuo   +8 more
core   +1 more source

Visible-Light Photoredox Catalysis in Water

The Journal of Organic Chemistry, 2022
The use of water in organic synthesis draws attention to its green chemistry features and its unique ability to unveil unconventional reactivities. Herein, literature about the use of water as a reaction medium under visible-light photocatalytic conditions is summarized in order to highlight challenges and opportunities.
Camilla Russo, Francesca Brunelli, Gian Cesare Tron, Mariateresa Giustiniano   +3 more
openaire   +4 more sources

From [NHC─H]• to Persistent σ‐Complex Radicals: Photoinduced Radical Chemistry of Imidazolium Salts

Angewandte Chemie, EarlyView.
Visible‐light excitation of electron donor–acceptor (EDA) complexes between imidazolium salts and triarylamines enables controlled single‐electron transfer (SET) and reveals a family of carbene‐centered σ‐complex radical cations. Cryogenic electron paramagnetic resonance (EPR) captures the elusive [NHC─H]• intermediate and its thermal evolution into ...
Filipp M. Kolomeychuk, Lars J. C. van der Zee, Simon Mathew, Bas de Bruin, J. Chris Slootweg   +4 more
wiley   +2 more sources

Controlling Near‐Infrared Fluorescence‐to‐Phosphorescence Ratios and Triplet Lifetimes in Rhodium(I) Dimers via Primary and Secondary Coordination Sphere Effects

Angewandte Chemie, EarlyView.
RhI dimers with bridging aryl isocyanide and di‐phosphine ligands show NIR‐I or NIR‐II fluorescence/phosphorescence, depending on the ligands and conformational rigidity at the Rh2 core. Rh‐Rh interactions can be tuned by peripheral modification of the aryl isocyanide ligand, resulting in a rigid Rh2 core and improved photophysical properties ...
Vanitha R. Naina, Giacomo Morselli, Alessandro Prescimone, Daniel Häussinger, Oliver S. Wenger   +4 more
wiley   +2 more sources

New‐Era Polymer Thermoelectrics: Material Innovations, Doping Frontiers, Decoupling Strategies, and Unconventional Applications

Advanced Materials, EarlyView.
The field of polymer thermoelectrics is entering a new era, featuring breakthroughs in addressing the conventional performance disparity between p‐type and n‐type polymers, pioneering doping frontiers, and sophisticated decoupling strategies. This review explores innovations in molecular design and superior stabilities, bridging the gap from ...
Suhao Wang
wiley   +1 more source

Visible light-mediated gold-catalysed carbon(sp2)-carbon(sp) cross-coupling. [PDF]

, 2016
A dual photoredox and gold-catalysed cross-coupling reaction of alkynyltrimethylsilanes and aryldiazonium tetrafluoroborates is described. The reaction proceeds through visible-light mediated oxidative addition of aryldiazoniums, transmetalation of ...
Kim, Suhong, Rojas-Martin, Jaime, Toste, F Dean   +2 more
core   +1 more source