Seven- and 23-year-old Siblings with Papulonodular Lesions after Sun Exposure: A Quiz
Davide Neri +4 more
doaj +1 more source
Biochemical and molecular diagnosis of erythropoietic protoporphyria in an Ashkenazi Jewish family [PDF]
Summary: Erythropoietic protoporphyria (EPP) is a rare hereditary disorder due to a partial deficiency of ferrochelatase (FECH). The genotype of EPP patients features a mutation on one allele of the FECH gene and a common hypomorphic FECH IVS3-48c on the
Mamet, R. +3 more
core
Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li +10 more
wiley +1 more source
Formoterol dynamically alters endocannabinoid tone in the periaqueductal gray inducing headache
Background Headache is a pain disorder present in populations world-wide with a higher incidence in females. Specifically, the incidences of medication overuse headache (MOH) have increased worldwide.
Ingrid L. Peterson +6 more
doaj +1 more source
Degeneration of human photosensitive retinal ganglion cells may explain sleep and circadian rhythms disorders in Parkinson’s disease [PDF]
Isabel Ortuño‐Lizarán +6 more
openalex +1 more source
This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong +10 more
wiley +1 more source
FUNDAMENTOS: As manifestações mucocutâneas são comuns em pacientes com lúpus eritematoso sistêmico,podendo assumir espectro bastante variado. OBJETIVOS: Estudar a prevalência de lesões mucocutâneas no lúpus eritematoso sistêmico e verificar suas ...
Ana Paula Bachtold Machado +3 more
doaj +1 more source
Recurrent Mutations in Kindlin-1, a Novel Keratinocyte Focal Contact Protein, in the Autosomal Recessive Skin Fragility and Photosensitivity Disorder, Kindler Syndrome [PDF]
G H S Ashton +15 more
openalex +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
The Coexistence of Systemic Lupus Erythematosus and Psoriasis: Is It Possible?
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with various clinical disorders and frequent exacerbations. Psoriasis vulgaris is a common skin disorder which affect 1-3% of general populations.
Hendra Gunawan +2 more
doaj +2 more sources

