Results 151 to 160 of about 44,543 (288)

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source

Construction of Modifiable Phthalocyanine-Based Covalent Organic Frameworks with Irreversible Linking for Efficient Photocatalytic CO₂ Reduction. [PDF]

Nanomicro Lett
Zhou X, Yang S, Hu Z, Chen Z, Guo Y, Wang T, Zhang Q, Zhang H.   +7 more
europepmc   +1 more source

Alkyl chain length-regulated in situ intelligent nano-assemblies with AIE-active photosensitizers for photodynamic cancer therapy

Lingyi Shen, Qi‐Long Zhang, Yongchao Yao, Yali Huang, Zhichang Zheng, Ming Li, Hong Xu, Lin Yuing Tan, Xukun Liao, Binyi Xia, Lin Li, Carl Redshaw, Yang Bai, Chengli Yang   +13 more
openalex   +1 more source

In vitro and in vivo targeted delivery of photosensitizers to the tumor cells for enhanced photodynamic effects

, 2011
Seema Gupta, Bilikere S. Dwarakanath, N. K. Chaudhury, AnilK Mishra, K. Muralidhar, Viney Jain   +5 more
openalex   +1 more source

Fluorinated Hypoxia‐Responsive Aza‐BODIPY for NIR‐II FL/19F MR/PA Imaging and Phototherapy of Lung Cancer

Advanced Science, EarlyView.
Fluorinated N‐oxide aza‐BODIPY nanoemulsions integrate fluorination‐driven molecular design with co‐assembly in fluorinated oil for multimodal imaging‐guided phototherapy. The co‐assembly redshifts fluorescence into the NIR‐II window for deep‐tissue imaging and provides a unified 19F signal for background‐free, quantitative MRI.
Anfeng Li, Fang Wang, Mou Jiang, Yu Li, Xin Zhou, Zhong‐Xing Jiang   +5 more
wiley   +1 more source

Effectiveness of Natural Photosensitizers in Antimicrobial Photodynamic Therapy Within Dentistry: A Systematic Review of RCTs. [PDF]

J Clin Med
Fiegler-Rudol J, Skaba D, Truchel D, Misiołek M, Wiench R.   +4 more
europepmc   +1 more source

Ultrafast Electron Transfer Coupled with a Proton Relay in an Anisotropic Dual S‐Scheme Heterojunction for Overcoming Kinetics Mismatch in H2O2 Photosynthesis

Advanced Science, EarlyView.
An anisotropic dual S‐scheme heterojunction (C3N4/SubPc‐1/C3N5) is constructed to overcome the electron–proton kinetics mismatch in photocatalytic H2O2 production. The imide bridge serves as a dual channel for ultrafast electron transfer and proton relay, synergistically enabling efficient dual‐pathway oxygen reduction and achieving a high H2O2 ...
Bing Wang, XiangBo Feng, Yao Liu, XinYi Wang, EnZhou Liu, YuZhen Zhao, ZongCheng Miao, Zhuo Li   +7 more
wiley   +1 more source

Flash Photodynamic Therapy - How the Saturation of Photosensitizer Absorption Enables Selective and Deeper Tumor Treatments. [PDF]

Adv Sci (Weinh)
Arnaut LG, Schaberle FA, Sereno J, Gomes-da-Silva LC.   +3 more
europepmc   +1 more source

Photodynamic Therapy for Glioblastoma: Potential Application of TiO2 and ZnO Nanoparticles as Photosensitizers [PDF]

Emma Ortiz, Ma. Elena Manríquez-Ramírez, Pedro Montes, Citlali Ekaterina Rodríguez-Pérez, Elizabeth Ruiz-Sánchez, Karla Carvajal, Victoria Campos‐Peña   +6 more
openalex   +1 more source

A Dual‐Piezoelectric Metal–Organic Cage/COF Z‐Scheme Heterojunction for Solar‐Mechanical Water Splitting

Advanced Science, EarlyView.
A dual‐piezoelectric Z‐scheme heterojunction is constructed by integrating a piezoelectric metal–organic cage (MOC‐FA3) with a β‐ketoenamine‐linked covalent organic framework (S‐COF). This design enables efficient solar‐mechanical energy conversion, achieving remarkable piezo‐photocatalytic pure water splitting for simultaneous H2 and H2O2 production ...
Xin‐Ao Li, Yixuan Wang, Zi‐Zhan Liang, Xin‐Bang Peng, Li‐Min Xiao, Li Gong, Xinyi Yang, Bo Zou, Yecheng Zhou, Jun‐Min Liu   +9 more
wiley   +1 more source