Results 151 to 160 of about 13,390 (349)

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

open access: yesAdvanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su   +18 more
wiley   +1 more source

Fluorinated Hypoxia‐Responsive Aza‐BODIPY for NIR‐II FL/19F MR/PA Imaging and Phototherapy of Lung Cancer

open access: yesAdvanced Science, EarlyView.
Fluorinated N‐oxide aza‐BODIPY nanoemulsions integrate fluorination‐driven molecular design with co‐assembly in fluorinated oil for multimodal imaging‐guided phototherapy. The co‐assembly redshifts fluorescence into the NIR‐II window for deep‐tissue imaging and provides a unified 19F signal for background‐free, quantitative MRI.
Anfeng Li   +5 more
wiley   +1 more source

Ultrafast Electron Transfer Coupled with a Proton Relay in an Anisotropic Dual S‐Scheme Heterojunction for Overcoming Kinetics Mismatch in H2O2 Photosynthesis

open access: yesAdvanced Science, EarlyView.
An anisotropic dual S‐scheme heterojunction (C3N4/SubPc‐1/C3N5) is constructed to overcome the electron–proton kinetics mismatch in photocatalytic H2O2 production. The imide bridge serves as a dual channel for ultrafast electron transfer and proton relay, synergistically enabling efficient dual‐pathway oxygen reduction and achieving a high H2O2 ...
Bing Wang   +7 more
wiley   +1 more source

A glance at imaging bladder cancer. [PDF]

open access: yes, 2018
Purpose: Early and accurate diagnosis of Bladder cancer (BCa) will contribute extensively to the management of the disease. The purpose of this review was to briefly describe the conventional imaging methods and other novel imaging modalities used for ...
Halpern, Ethan J.   +4 more
core   +1 more source

A Dual‐Piezoelectric Metal–Organic Cage/COF Z‐Scheme Heterojunction for Solar‐Mechanical Water Splitting

open access: yesAdvanced Science, EarlyView.
A dual‐piezoelectric Z‐scheme heterojunction is constructed by integrating a piezoelectric metal–organic cage (MOC‐FA3) with a β‐ketoenamine‐linked covalent organic framework (S‐COF). This design enables efficient solar‐mechanical energy conversion, achieving remarkable piezo‐photocatalytic pure water splitting for simultaneous H2 and H2O2 production ...
Xin‐Ao Li   +9 more
wiley   +1 more source

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