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Photodynamic Therapy with a New Photosensitizing Agent
Photomedicine and Laser Surgery, 2007Objective: The aim of this study was to investigate the cytotoxicity of octal-bromide zinc phthalocyanine (ZnPcBr 8 ) before and after irradiation with a low-power laser (AsGaAl) and analyze the effects of photodynamic therapy (PDT) on the nucleus of L929 cells.
Aline Helena Araujo, Machado +5 more
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Photosensitizers Binding to Nucleic Acids as Anticancer Agents
Future Medicinal Chemistry, 2016Cationic porphyrins (Prs) and phthalocyanines (Pcs) are strong photosensitizers that have drawn much attention for their potential in photodynamic therapy. These compounds have the interesting property of binding to nucleic acids, in particular G-rich quadruplex-forming sequences in DNA and RNA.
XODO, Luigi +2 more
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Eradication of Acinetobacter baumannii by photosensitized agents in vitro
Journal of Photochemistry and Photobiology B: Biology, 1998The photodynamic effects of photosensitizers on Acinetobacter baumannii were studied. These Gram negative bacteria have recently been implicated in various infections, mainly acquired in hospitals. They have outstanding characteristics of multidrug high resistance to antimicrobial agents. The best photodynamic effect was obtained when A.
Y, Nitzan +2 more
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Cutaneous photosensitivity diseases induced by exogenous agents
Journal of the American Academy of Dermatology, 1995Cutaneous photosensitivity diseases may be idiopathic, produced by endogenous photosensitizers, or associated with exogenous photosensitizers. Those caused by exogenous agents include phototoxicity, photoallergy, and the exacerbation or induction of systemic disorders in which photosensitivity is a prominent clinical manifestation. Phototoxic disorders
J W, Gould, M G, Mercurio, C A, Elmets
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IS PENICILLIN A PHOTOSENSITIZING AGENT?
Archives of Dermatology, 1945It is a well known fact that penicillin therapy produces few reactions. Urticaria seems to be the most common cutaneous reaction. In this report the possibility is suggested that penicillin acts as a photosensitizing agent. Photodermatitis of vegetable origin has already been well studied.1It is due in most instances to external contact of the patient
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Synthesis of Porphyrin‐Anthraquinone Conjugates as Photosensitizing Agents
Synthetic Communications, 2008Stefano Banfi +2 more
exaly +3 more sources
Photosensitizers as virucidal agents.
Journal of photochemistry and photobiology. B, Biology, 1993The photosensitizer, benzoporphyrin derivative monoacid ring A (BPD-MA) has been studied regarding its ability to destroy enveloped viruses in blood and blood products when activated by light. Its maximum wavelength of absorption (690 nm) has proven useful in terms of activation of the photosensitizer in materials containing red blood cells ...
J, North, H, Neyndorff, J G, Levy
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A carbohydrate-linked hypericinic photosensitizing agent
Monatshefte für Chemie - Chemical Monthly, 2008With respect to an enhanced solubility under physiological conditions, a carbohydrate-containing hypericin-based second-generation photosensitizer was prepared. Its photochemical properties were tested by means of the light-sensitized destruction of bilirubin IXα to be even better than those of the parent compound hypericin.
Joachim Zuschrader +2 more
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Free Radical Biology and Medicine, 1988
Single-strand breaks can be introduced into PM2 closed-circular DNA upon illumination with blue light, in the presence of the anthrapyrazole antitumor agent, compound 1. Damage is observed already after 1 min of blue light illumination, and is significantly enhanced by the presence of electron donors such as NADH, ascorbic acid or Fe(III)/EDTA complex.
J A, Hartley, K, Reszka, J W, Lown
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Single-strand breaks can be introduced into PM2 closed-circular DNA upon illumination with blue light, in the presence of the anthrapyrazole antitumor agent, compound 1. Damage is observed already after 1 min of blue light illumination, and is significantly enhanced by the presence of electron donors such as NADH, ascorbic acid or Fe(III)/EDTA complex.
J A, Hartley, K, Reszka, J W, Lown
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[Exogenous photosensitizing agents].
La Revue du praticien, 1992The frequent use of remedies either in topical or systemic form has led to a rising number of photosensitizations. The different cutaneous manifestations of exogenous photosensitizers e.g. phototoxicity and photoallergy, are described. We treat the most important agents of these reactions and lay stress upon the patient's interview and the phototesting
C, Loesche, O, Podglajen, P, Thomas
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