Results 261 to 270 of about 13,262 (302)

IS PENICILLIN A PHOTOSENSITIZING AGENT?

Archives of Dermatology, 1945
It is a well known fact that penicillin therapy produces few reactions. Urticaria seems to be the most common cutaneous reaction. In this report the possibility is suggested that penicillin acts as a photosensitizing agent. Photodermatitis of vegetable origin has already been well studied.1It is due in most instances to external contact of the patient
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Photosensitization by antitumor agents 2: Anthrapyrazole-photosensitized oxidation of ascorbic acid and 3,4-dihydroxyphenylalanine

Journal of Free Radicals in Biology & Medicine, 1986
A novel anthrapyrazole anticancer agent has been examined for photosensitizing properties. Illumination of the anthrapyrazole and ascorbic acid with blue light in aerated aqueous solutions causes SOD and catalase-sensitive oxygen consumption, indicating involvement of both superoxide radical and hydrogen peroxide in this process.
K, Reszka, P, Kolodziejczyk, J W, Lown
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TREATMENT OF PSORIASIS WITH PHOTOSENSITIZING AGENTS

Archives of Dermatology and Syphilology, 1941
The sun's rays appear to be valuable in the treatment of psoriasis, and in most cases the condition improves during the summer months. In many cases of extensive lesions with indurated plaques and in cases in which the condition becomes aggravated rather than improved in the summer, it is possible that the skin is not photosensitive.
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Eradication of Acinetobacter baumannii by photosensitized agents in vitro

Journal of Photochemistry and Photobiology B: Biology, 1998
The photodynamic effects of photosensitizers on Acinetobacter baumannii were studied. These Gram negative bacteria have recently been implicated in various infections, mainly acquired in hospitals. They have outstanding characteristics of multidrug high resistance to antimicrobial agents. The best photodynamic effect was obtained when A.
Y, Nitzan, A, Balzam-Sudakevitz, H, Ashkenazi   +2 more
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Photosensitization by anticancer agents 21: New perylene- and aminonaphthoquinones

Free Radical Biology and Medicine, 1996
Hypocrellins are under intensive investigation as photosensitizing agents for photodynamic therapy (PDT). A recent advance in the synthesis of hypocrellin congeners resulted in the production of an amino-substituted hypocrellin-B, and its "half chromophore." Both compounds exhibit stronger red light absorption than previously reported hypocrellins, and,
Z J, Diwu, R P, Haugland, J, Liu, J W, Lown, G G, Miller, R B, Moore, K, Brown, J, Tulip, M S, McPhee   +8 more
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[Phototherapy of tumors using photosensitizing agents].

Eksperimental'naia onkologiia, 1988
The experimental and clinical data on a new method of cancer treatment--photodestruction of tumours treated with the photosensitizing preparations--are reviewed. Particular emphasis is given to porphyrin compounds. The problems are considered dealing with accumulation of these compounds in cells and tissues, with the mechanism of photoalteration of ...
N F, Gamalev, I A, Mikhalkin
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Porphyrins as Antimicrobial Photosensitizing Agents

2013
The emergence of microbial resistance to many of the major classes of antimicrobial drugs is becoming an increasing problem in the clinic and environmental areas. As such, the discovery of drugs with novel modes of action will be vital to meet the threats created by the emergence of resistance.
Almeida, A., Cunha, A., Faustino, M. A. F., Tomé, A. C., Neves, M. G. P. M. S.   +4 more
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SULFANILAMIDE: A PHOTOSENSITIZING AGENT OF THE SKIN

Journal of the American Medical Association, 1937
In spite of the intensive use of sulfanilamide in the last year as a chemotherapeutic agent in beta-hemolytic streptococcus infections, clinical reports have noted a relatively low incidence of untoward reactions. Our observations of more than 300 patients in the erysipelas wards of Bellevue Hospital (service of Dr.
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GABAergic agents as anticonvulsants in baboons with photosensitive epilepsy

Neuroscience Letters, 1984
GABAergic agents have been evaluated for acute anticonvulsant activity in baboons, Papio papio with photosensitive epilepsy. The potent GABAA agonists muscimol and THIP are proconvulsant. (-)Baclofen, 2 mg/kg suppresses myoclonic responses; higher doses facilitate EEG paroxysmal activity.
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Contact Photosensitivity Dermatitis From Sun-protective Agent

Archives of Dermatology, 1969
A popular commercial sunscreening agent containing the ultraviolet-absorbing chemical glycerylp-aminobenzoate was found to be a photosensitizer having produced a severe dermatitis in a patient who applied it prior to sun exposure. Three possible mechanisms of action are briefly discussed: photoallergy, phototoxicity, and photoaugmentation.
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