Results 251 to 260 of about 9,311 (277)

Photosensitization by antitumor agents 2: Anthrapyrazole-photosensitized oxidation of ascorbic acid and 3,4-dihydroxyphenylalanine

Journal of Free Radicals in Biology & Medicine, 1986
A novel anthrapyrazole anticancer agent has been examined for photosensitizing properties. Illumination of the anthrapyrazole and ascorbic acid with blue light in aerated aqueous solutions causes SOD and catalase-sensitive oxygen consumption, indicating involvement of both superoxide radical and hydrogen peroxide in this process.
K, Reszka, P, Kolodziejczyk, J W, Lown
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SULFANILAMIDE: A PHOTOSENSITIZING AGENT OF THE SKIN

Journal of the American Medical Association, 1937
In spite of the intensive use of sulfanilamide in the last year as a chemotherapeutic agent in beta-hemolytic streptococcus infections, clinical reports have noted a relatively low incidence of untoward reactions. Our observations of more than 300 patients in the erysipelas wards of Bellevue Hospital (service of Dr.
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A tumor mRNA-mediated bi-photosensitizer molecular beacon as an efficient imaging and photosensitizing agent

Chemical Communications, 2011
A bi-photosensitizer molecular beacon (bi-PS MB) is assembled by coupling two PS molecules, respectively, onto the opposite ends of a single MB. The MB can be triggered by a tumor marker-survivin mRNA. Fluorescence and cytotoxic (1)O(2) generation occur effectively in breast cancer cells, but not in normal cells.
Yuan, Gao, Guangming, Qiao, Linhai, Zhuo, Na, Li, Ying, Liu, Bo, Tang   +5 more
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SPECTROSCOPIC STUDIES OF CUTANEOUS PHOTOSENSITIZING AGENTS. XVII. BENZANTHRONE

Photochemistry and Photobiology, 1992
Abstract—The photochemistry of benzanthrone (7H‐benz[de]‐anthracene‐7‐one) has been studied using electron paramagnetic resonance (EPR) in conjunction with the spin trapping technique and the direct detection of singlet molecular oxygen luminescence.
R, Dabestani, R H, Sik, A G, Motten, C F, Chignell   +3 more
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SPECTROSCOPIC STUDIES OF CUTANEOUS PHOTOSENSITIZING AGENTS. XVIII. INDOMETHACIN

Photochemistry and Photobiology, 1993
Abstract—The photochemistry, photophysics, and photosensitization (Type I and II) of indomethacin (IN) (N‐[p‐chlorobenzoyl]‐5‐methoxy‐2‐methylindole‐3‐acetic acid) has been studied in a variety of solvents using NMR, high performance liquid chromatography‐mass spectroscopy, transient spectroscopy, electron paramagnetic resonance in conjunction with the
R, Dabestani, R H, Sik, D G, Davis, G, Dubay, C F, Chignell   +4 more
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GABAergic agents as anticonvulsants in baboons with photosensitive epilepsy

Neuroscience Letters, 1984
GABAergic agents have been evaluated for acute anticonvulsant activity in baboons, Papio papio with photosensitive epilepsy. The potent GABAA agonists muscimol and THIP are proconvulsant. (-)Baclofen, 2 mg/kg suppresses myoclonic responses; higher doses facilitate EEG paroxysmal activity.
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Extensive Burns Caused by the Abusive Use of Photosensitizing Agents

Journal of Burn Care & Rehabilitation, 1997
Psoralens are photosensitizing agents used in dermatology as reinforcements in psoralen ultraviolet A-range therapy. We report observations of 14 young women hospitalized for severe burns caused by abusive use of psoralens. The burns were of superficial and deep second-degree depth and covered more than 76% of the body surface on average.
F, Braye, J, Latarjet, J L, Foyatier, J P, Comparin, P, Tranchand, C, Boucaud   +5 more
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Photosensitization by anticancer agents 21: New perylene- and aminonaphthoquinones

Free Radical Biology and Medicine, 1996
Hypocrellins are under intensive investigation as photosensitizing agents for photodynamic therapy (PDT). A recent advance in the synthesis of hypocrellin congeners resulted in the production of an amino-substituted hypocrellin-B, and its "half chromophore." Both compounds exhibit stronger red light absorption than previously reported hypocrellins, and,
Z J, Diwu, R P, Haugland, J, Liu, J W, Lown, G G, Miller, R B, Moore, K, Brown, J, Tulip, M S, McPhee   +8 more
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[Phototherapy of tumors using photosensitizing agents].

Eksperimental'naia onkologiia, 1988
The experimental and clinical data on a new method of cancer treatment--photodestruction of tumours treated with the photosensitizing preparations--are reviewed. Particular emphasis is given to porphyrin compounds. The problems are considered dealing with accumulation of these compounds in cells and tissues, with the mechanism of photoalteration of ...
N F, Gamalev, I A, Mikhalkin
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Porphyrins as Antimicrobial Photosensitizing Agents

2013
The emergence of microbial resistance to many of the major classes of antimicrobial drugs is becoming an increasing problem in the clinic and environmental areas. As such, the discovery of drugs with novel modes of action will be vital to meet the threats created by the emergence of resistance.
Almeida, A., Cunha, A., Faustino, M. A. F., Tomé, A. C., Neves, M. G. P. M. S.   +4 more
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