Results 251 to 260 of about 13,262 (302)
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Cutaneous photosensitivity diseases induced by exogenous agents
Journal of the American Academy of Dermatology, 1995Cutaneous photosensitivity diseases may be idiopathic, produced by endogenous photosensitizers, or associated with exogenous photosensitizers. Those caused by exogenous agents include phototoxicity, photoallergy, and the exacerbation or induction of systemic disorders in which photosensitivity is a prominent clinical manifestation. Phototoxic disorders
J W, Gould, M G, Mercurio, C A, Elmets
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IS PENICILLIN A PHOTOSENSITIZING AGENT?
Archives of Dermatology, 1946To the Editor :—Under the title "Is Penicillin a Photosensitizing Agent?" Dr. Orlando Canizares (Arch. Dermat. & Syph. 52 :17 [July] 1945) reports on an interesting case. Since penicillin is such an important drug, the question whether it is also a photosensitizer deserves careful attention; therefore, I should like to comment briefly on Dr. Canizares'
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Photosensitizers Binding to Nucleic Acids as Anticancer Agents
Future Medicinal Chemistry, 2016Cationic porphyrins (Prs) and phthalocyanines (Pcs) are strong photosensitizers that have drawn much attention for their potential in photodynamic therapy. These compounds have the interesting property of binding to nucleic acids, in particular G-rich quadruplex-forming sequences in DNA and RNA.
XODO, Luigi +2 more
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A carbohydrate-linked hypericinic photosensitizing agent
Monatshefte für Chemie - Chemical Monthly, 2008With respect to an enhanced solubility under physiological conditions, a carbohydrate-containing hypericin-based second-generation photosensitizer was prepared. Its photochemical properties were tested by means of the light-sensitized destruction of bilirubin IXα to be even better than those of the parent compound hypericin.
Joachim Zuschrader +2 more
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[Exogenous photosensitizing agents].
La Revue du praticien, 1992The frequent use of remedies either in topical or systemic form has led to a rising number of photosensitizations. The different cutaneous manifestations of exogenous photosensitizers e.g. phototoxicity and photoallergy, are described. We treat the most important agents of these reactions and lay stress upon the patient's interview and the phototesting
C, Loesche, O, Podglajen, P, Thomas
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SPECTROSCOPIC STUDIES OF CUTANEOUS PHOTOSENSITIZING AGENTS. XVII. BENZANTHRONE
Photochemistry and Photobiology, 1992Abstract—The photochemistry of benzanthrone (7H‐benz[de]‐anthracene‐7‐one) has been studied using electron paramagnetic resonance (EPR) in conjunction with the spin trapping technique and the direct detection of singlet molecular oxygen luminescence.
R, Dabestani +3 more
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Preclinical Evaluation Of Photosensitizing Agents
SPIE Proceedings, 1989Methods for the pre-clinical evaluation of new photosensitizing dyes are described. The resulting information can provide useful leads concerning likely modes and sites of localization. But correlations between results obtained in cell culture and in animal tumor models are sufficiently weak to indicate the need for caution in extrapolation of any in ...
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SPECTROSCOPIC STUDIES OF CUTANEOUS PHOTOSENSITIZING AGENTS. XVIII. INDOMETHACIN
Photochemistry and Photobiology, 1993Abstract—The photochemistry, photophysics, and photosensitization (Type I and II) of indomethacin (IN) (N‐[p‐chlorobenzoyl]‐5‐methoxy‐2‐methylindole‐3‐acetic acid) has been studied in a variety of solvents using NMR, high performance liquid chromatography‐mass spectroscopy, transient spectroscopy, electron paramagnetic resonance in conjunction with the
R, Dabestani +4 more
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Photosensitizers as virucidal agents.
Journal of photochemistry and photobiology. B, Biology, 1993The photosensitizer, benzoporphyrin derivative monoacid ring A (BPD-MA) has been studied regarding its ability to destroy enveloped viruses in blood and blood products when activated by light. Its maximum wavelength of absorption (690 nm) has proven useful in terms of activation of the photosensitizer in materials containing red blood cells ...
J, North, H, Neyndorff, J G, Levy
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Free Radical Biology and Medicine, 1988
Single-strand breaks can be introduced into PM2 closed-circular DNA upon illumination with blue light, in the presence of the anthrapyrazole antitumor agent, compound 1. Damage is observed already after 1 min of blue light illumination, and is significantly enhanced by the presence of electron donors such as NADH, ascorbic acid or Fe(III)/EDTA complex.
J A, Hartley, K, Reszka, J W, Lown
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Single-strand breaks can be introduced into PM2 closed-circular DNA upon illumination with blue light, in the presence of the anthrapyrazole antitumor agent, compound 1. Damage is observed already after 1 min of blue light illumination, and is significantly enhanced by the presence of electron donors such as NADH, ascorbic acid or Fe(III)/EDTA complex.
J A, Hartley, K, Reszka, J W, Lown
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