Rotaxanes with integrated photoswitches: design principles, functional behavior, and emerging applications [PDF]
Beilstein Journal of Organic ChemistryIntegrating molecular photoswitches into rotaxanes offers unique opportunities for precise control over their structural, dynamic, and functional properties.
Jullyane Emi Matsushima +4 more
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Photoswitches beyond azobenzene: a beginner’s guide [PDF]
Beilstein Journal of Organic ChemistryApproaching the vast, colourful world of photoswitches from a different field of study or as an undergraduate student may be overwhelming: azobenzene is undoubtedly the most famous due to its easy synthesis and the extensively studied properties. However,
Michela Marcon +2 more
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Synthesis and Study of Substituted Chalcones Combined with Fluoroazobenzenes—New Photoswitches for Application in Biological Systems [PDF]
MoleculesChalcones have garnered significant research interest due to their various medical bioactivities. Several chalcone compounds have been approved for marketing and clinical use in the treatment of various diseases.
Piotr Tobiasz +5 more
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Substituent effects in N-acetylated phenylazopyrazole photoswitches [PDF]
Beilstein Journal of Organic ChemistryPhenylazopyrazole photoswitches proved to be valuable structural motifs for various applications ranging from materials science to medicine. Despite their potential, their structural diversity is still limited and a larger pool of substitution patterns ...
Radek Tovtik +4 more
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Exploiting negative photochromism to harness a four-photon-like fluorescence response with two-photon excitation [PDF]
Nature CommunicationsCombining nonlinear optical processes and photoswitching transcends the limitations of conventional and even standalone super-resolution imaging. While photoswitching enables resolution improvement, it is typically constrained by limited imaging depth ...
Carlos Benitez-Martin +7 more
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Understanding Photomechanical Behavior of Liquid Crystalline‐Based Actuators
Macromolecular Materials and Engineering, 2023 Liquid crystalline‐based actuators containing azobenzene photoswitches have been used to demonstrate light‐responsive motion in soft actuator systems.
Jasleen Lall, Hans Zappe
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Two-Photon Excitation of Azobenzene Photoswitches for Synthetic Optogenetics
Applied Sciences, 2020 Synthetic optogenetics is an emerging optical technique that enables users to photocontrol molecules, proteins, and cells in vitro and in vivo. This is achieved by use of synthetic chromophores—denoted photoswitches—that undergo light ...
Shai Kellner, Shai Berlin
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Light-Activating PROTACs in Cancer: Chemical Design, Challenges, and Applications
Applied Sciences, 2022 Nonselective cell damage remains a significant limitation of radiation therapies in cancer. Decades of successful integration of radiation therapies with other medicinal chemistry strategies significantly improved therapeutic benefits in cancer ...
Arvind Negi +2 more
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First-in-Class Colchicine-Based Visible Light Photoswitchable Microtubule Dynamics Disrupting Agent
Cells, 2023 Compounds that disrupt microtubule dynamics, such as colchicine, paclitaxel, or Vinca alkaloids, have been broadly used in biological studies and have found application in clinical anticancer medications.
Filip Borys +4 more
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Design and Tuning of Photoswitches for Solar Energy Storage
Molecules, 2021 Current energy demand makes it compulsory to explore alternative energy sources beyond fossil fuels. Molecular solar thermal (MOST) systems have been proposed as a suitable technology for the use and storage of solar energy.
Raul Losantos, Diego Sampedro
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