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Two-Photon Excitation of Azobenzene Photoswitches for Synthetic Optogenetics
Applied Sciences, 2020 Synthetic optogenetics is an emerging optical technique that enables users to photocontrol molecules, proteins, and cells in vitro and in vivo. This is achieved by use of synthetic chromophores—denoted photoswitches—that undergo light ...
Shai Kellner, Shai Berlin
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Photoswitches Beyond Azobenzene: A Beginner’s Guide
Beilstein Journal of Organic ChemistryApproaching the vast, colourful world of photoswitches from a different field of study or as an undergraduate student may be overwhelming: azobenzene is undoubtedly the most famous due to its easy synthesis and the extensively studied properties. However,
Michela Marcon +2 more
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Photopharmacology Beyond Azobenzene Photoswitches
Responsive materialsPhotopharmacology harnesses photoswitchable molecules to reversibly and precisely modulate biological activities, offering exceptional spatial and temporal control through non‐invasive illumination.
Junji Zhang, Jinghong Dai
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Understanding Photomechanical Behavior of Liquid Crystalline‐Based Actuators
Macromolecular Materials and Engineering, 2023 Liquid crystalline‐based actuators containing azobenzene photoswitches have been used to demonstrate light‐responsive motion in soft actuator systems.
Jasleen Lall, Hans Zappe
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Design and Tuning of Photoswitches for Solar Energy Storage
Molecules, 2021 Current energy demand makes it compulsory to explore alternative energy sources beyond fossil fuels. Molecular solar thermal (MOST) systems have been proposed as a suitable technology for the use and storage of solar energy.
Raul Losantos, Diego Sampedro
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Photoresponsive Adhesives Based on Arylazoisoxazoles‐Containing Polymers
Macromolecular Materials and Engineering, 2023 Adhesives exist in many forms and are essential in the daily life, in industrial processes, and in healthcare, calling for continuous improvements in terms of application fields, strength, biocompatibility, recyclability, and reversibility. Regarding the
Ruggero Rossi +6 more
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Light-Activating PROTACs in Cancer: Chemical Design, Challenges, and Applications
Applied Sciences, 2022 Nonselective cell damage remains a significant limitation of radiation therapies in cancer. Decades of successful integration of radiation therapies with other medicinal chemistry strategies significantly improved therapeutic benefits in cancer ...
Arvind Negi +2 more
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First-in-Class Colchicine-Based Visible Light Photoswitchable Microtubule Dynamics Disrupting Agent
Cells, 2023 Compounds that disrupt microtubule dynamics, such as colchicine, paclitaxel, or Vinca alkaloids, have been broadly used in biological studies and have found application in clinical anticancer medications.
Filip Borys +4 more
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IEEE Journal of Translational Engineering in Health and Medicine, 2023 Optogenetics is a new approach for controlling neural circuits with numerous applications in both basic and clinical science. In retinal degenerative diseases, the photoreceptors die, but inner retinal cells remain largely intact.
Boyuan Yan, Sheila Nirenberg
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Orthogonal photoswitching in a multifunctional molecular system
Nature Communications, 2016 While molecular photoswitches have proven useful in many fields, selective and reversible control over multiple switches is an unsolved challenge. Here, the authors report on a system consisting of two classes of photoswitches that can be addressed ...
Michael M. Lerch +4 more
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