Results 61 to 70 of about 6,232 (230)

Deciphering Small Molecule Diffusion Parameters Across Light Responsive Polymersome Membranes

Advanced Functional Materials, EarlyView.
Light‐responsive polymersomes bearing donor–acceptor Stenhouse adducts (DASAs) enable programmable control over small‐molecule transport across synthetic membranes. By systematically varying DASA density, an optimal functionalization regime is identified that maximizes light‐gated permeability.
Farzina Matubbar, Beyzanur Kaya, Buse Ipek, Tenzin Dorjee, Shoghik Hakobyan, Mohamed Chami, Julien E. Gautrot, Omar Rifaie‐Graham   +7 more
wiley   +1 more source

Optical Control of Metabotropic Glutamate Receptors [PDF]

, 2013
G-protein coupled receptors (GPCRs), the largest family of membrane signaling proteins, respond to neurotransmitters, hormones and small environmental molecules. The neuronal function of many GPCRs has been difficult to resolve because of an inability to
A Panatier, A Raveh, Adam Hoagland, Alexander F Schier, Andreas Reiner, B Altinbilek, B Lin, Benjamin Gaub, BK Kobilka, Brian Kane, BV Zemelman, C Grabher, C Lüscher, Carlos Pantoja, CM Niswender, David Schoppik, Dirk Trauner, DV Gutierrez, E Oh, Ehud Y Isacoff, G Chang, GA Kaminski, GJ Marek, GM Alexander, H Janovjak, HA Burgess, Harald Janovjak, HJ Bailes, IW Davis, J Bockaert, JA Saugstad, JL Leaney, JM Bekkers, JM Kim, Joshua Levitz, K Deisseroth, KL Pierce, KM Kwan, L Bordoli, L Hanna, L Iacovelli, M Banghart, M Koch, M Vivaudou, M Volgraf, MU Ehrengruber, N Caporale, P Gorostiza, Philipp Stawski, R Anwyl, R Kurita, R Shigemoto, RD Airan, RR Gainetdinov, S Szobota, SJ Bradley, SM Grauer, SR Ikeda, T Fehrentz, T Muto, T Takahashi, T Tsuji, T Yamashita, T Yamashita, X Li, X Qiu, Y Pei, Y Tanabe, Z Melyan   +68 more
core   +1 more source

Photo‐Controlled Antibacterial Drug Release From DASA‐Coated Silica Particles for Improved Treatment of Wound Infections

Advanced Functional Materials, EarlyView.
Synthesis and characterization of light‐responsive donor–acceptor Stenhouse adducts (DASA)‐coated chlorhexidine‐loaded silica nanoparticles. Such a controllable drug‐delivery system enables the release of the antimicrobial drug on demand and in consecutive cycles, thereby maintaining the concentration within the therapeutic window.
Michèle Clerc, Flavia Zuber, Lea Oberhänsli, Yvonne Elbs‐Glatz, Maria M. Miguel, Vera M. Kissling, Qun Ren, Markus Rottmar, Luciano F. Boesel, Giorgia Giovannini   +9 more
wiley   +1 more source

Photoswitchable Spasers with a Plasmonic Core and Photoswitchable Fluorescent Proteins [PDF]

Scientific Reports, 2019
AbstractPhotoswitchable fluorescent proteins (PFPs) that can change fluorescence color upon excitation have revolutionized many applications of light such as tracking protein movement, super-resolution imaging, identification of circulating cells, and optical data storage. Nevertheless, the relatively weak fluorescence of PFPs limits their applications
Walter N. Harrington, Marina V. Novoselova, Daniil N. Bratashov, Boris N. Khlebtsov, Dmitry A. Gorin, Ekaterina I. Galanzha, Vladimir P. Zharov   +6 more
openaire   +2 more sources

Azobenzene photocontrol of peptides and proteins [PDF]

, 2016
The last few years have witnessed significant advances in the use of light as a stimulus to control biomolecular interactions. Great efforts have been devoted to the development of genetically encoded optobiological and small photochromic switches. Newly
Allemann, Rudolf, Mart, Robert
core   +1 more source

Light‐Programmable Interfaces: From Molecular Photoswitching to Adaptive Membrane Separations

Advanced Materials Interfaces, EarlyView.
This review advances an interface‐centered framework for light‐responsive membranes, linking molecular photoswitches (azobenzene (AZO), spiropyran (SP), diarylethene (DAE), donor–acceptor Stenhouse adducts (DASA), photoacid) to integration strategies in polymeric, porous, self‐assembled, and mixed‐matrix systems.
Liangliang Zhang, Senlin Gu, Jianyang Zhao, Xiaojuan Hao, Lu Hua Li, Jihua Li, Lingxue Kong   +6 more
wiley   +1 more source

Beads, boats and switches: making things happen with molecular photoswitches [PDF]

, 2009
In this paper we present recent results obtained with a stimulus-responsive materials based on the photo-switchable behaviour exhibited by spiro-cyclic derivatives.
Benito-Lopez, Fernando, Byrne, Robert, Diamond, Dermot, Higgins, Michael, Scarmagnani, Silvia, Wallace, Gordon   +5 more
core   +1 more source

Optical control of NMDA-receptors with a diffusible photoswitch [PDF]

, 2015
N-methyl-D-aspartate receptors (NMDARs) play a central role in synaptic plasticity, learning and memory, and are implicated in various neuronal disorders.
Di Gregorio, David, Franckevicius, Vilius, Hartrampf, Felix, Hollmann, M., Laprell, Laura, Rebola, Nelson, Repak, Emilienne, Sumser, Martin, Terhag, Jan, Trauner, Dirk   +9 more
core   +4 more sources

Phototunable Polarization Volume Gratings Driven by Chiral Hydrazone Switches

Advanced Optical Materials, EarlyView.
Chiral hydrazone photoswitches incorporated into polarization volume gratings enable light‐driven, reversible modulation of optical properties. UV and blue light irradiation reversibly alter the hydrazone isomer ratio, leading to tunable diffraction efficiency and spectral response across the visible spectrum.
Artem Boichuk, Lauri Uosukainen, Indu Bala, Ivan Aprahamian, Arri Priimagi   +4 more
wiley   +1 more source

Design of a Photoswitchable Cadherin [PDF]

Journal of the American Chemical Society, 2013
There is a growing interest in engineering proteins whose function can be controlled with the spatial and temporal precision of light. Here, we present a novel example of a functional light-triggered switch in the Ca-dependent cell-cell adhesion protein E-cadherin, created using a mechanism-based design strategy. We report an 18-fold change in apparent
Kortemme, Tanja, Ritterson, RS, Kuchenbecker, KM, Michalik, M   +3 more
openaire   +4 more sources