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Graphene as Photothermal Therapeutic Agents

2022
Light-assisted hyperthermic therapy is a promising strategy to treat cancer. Graphene and their derivatives with unique physiochemical properties, intrinsic near infrared absorption, and ability to transduce the absorbed light energy into heat, have attracted researchers to use them for photothermal therapy (PTT).
Vishnu, Revuri   +2 more
openaire   +2 more sources

Organelle-targeted photothermal agents for cancer therapy

Chemical Communications, 2021
This feature article summarizes the recent advances in organelle-targeted PTT agents over the past ten years.
Eunbin Hwang, Hyo Sung Jung
openaire   +2 more sources

A Protein-Binding Molecular Photothermal Agent for Tumor Ablation

Angewandte Chemie - International Edition, 2021
AbstractPhotothermal therapy usually requires a high power density to activate photothermal agent for effective treatment, which inevitably leads to damage to normal tissues and inflammation in tumor tissues. Herein, we rationally design a protein‐binding strategy to build a molecular photothermal agent for photothermal ablation of tumor.
Ping Zhou, Yuanyuan Chen, Wei Pan
exaly   +3 more sources

A mitochondria-targeted thiazoleorange-based photothermal agent for enhanced photothermal therapy for tumors

Bioorganic Chemistry, 2021
Organic small molecules with near-infrared (NIR) absorption hold great promise as the phototheranostic agents for clinical translation by virtue of their inherent merits such as well-defined chemical structure, high purity and good reproducibility. Probes that happen to be based on cyanine dyes exhibit strong NIR-absorbing and efficient photothermal ...
Wangqing, Bian   +11 more
openaire   +2 more sources

A Borondifluoride-Complex-Based Photothermal Agent With an 80 % Photothermal Conversion Efficiency for Photothermal Therapy in the NIR-II Window

Angewandte Chemie - International Edition, 2021
Abstract Small organic photothermal agents (SOPTAs) that absorb in the second near‐infrared (NIR‐II, 1000–1700 nm) window are highly desirable in photothermal therapy for their good biocompatibility and deeper tissue penetration. However, the design of NIR‐II absorbing SOPTAs remains a great challenge.
Yuncong Chen   +2 more
exaly   +3 more sources

Fe-involved nanostructures act as photothermal transduction agents in cancer photothermal therapy

Colloids and Surfaces B: Biointerfaces, 2023
Cancer, a disease notorious for its difficult therapy regimen, has long puzzled researchers. Despite attempts to cure cancer using surgery, chemotherapy, radiotherapy, and immunotherapy, their effectiveness is limited. Recently, photothermal therapy (PTT), a rising strategy, has gained attention.
Zewei, Jiang   +6 more
openaire   +2 more sources

A Dual‐Targeted Organic Photothermal Agent for Enhanced Photothermal Therapy

Angewandte Chemie International Edition, 2018
AbstractThe development of highly effective anticancer drugs that cause minimal damage to the surrounding normal tissues is a challenging topic in cancer therapy. Herein, we demonstrate a dual‐targeted organic molecule that functions as a photothermal agent by actively targeting tumor tissue and mitochondria to selectively kill cancer cells.
Hongyu Wang   +5 more
openaire   +2 more sources

Tunable Nanostructures as Photothermal Theranostic Agents

Annals of Biomedical Engineering, 2011
The theranostic potential of several nanostructures has been discussed in the context of photothermal therapies and imaging. In the last several decades, the burden of cancer has grown rapidly, making the need for new theranostic approaches vital. Lasers have emerged as promising tools in cancer treatment, especially with the advent of photothermal ...
Joseph K, Young   +2 more
openaire   +2 more sources

Non-plasmonic NIR-Activated Photothermal Agents for Photothermal Therapy

2020
Photothermal therapies rely on various types of optically active nanomaterials, such as carbon, silicon, titanium dioxide, iron-based, polymeric, and rare earth-doped nanomaterials, which are aiming to convert light into heat. However, lack of clear guidelines and standardized approaches to determine their photothermal properties hinders quantitative ...
L. Marciniak   +3 more
openaire   +1 more source

Cu7.2S4 nanocrystals: a novel photothermal agent with a 56.7% photothermal conversion efficiency for photothermal therapy of cancer cells

Nanoscale, 2014
Copper sulphides, as a novel kind of photothermal agent for photothermal therapy (PTT) of cancer cells, have attracted increasing attention in recent years due to good photostability, synthetic simplicity, low toxicity and low cost. However, the unsatisfactory photothermal conversion efficiency of copper sulphides limits their bioapplication as PTT ...
Bo, Li   +6 more
openaire   +2 more sources

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