Results 181 to 190 of about 34,272 (324)

Activatable smart contrast agents for photoacoustic imaging

Smart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh, Jihye Lee, Suyoung Park, Juyoung Yoon, Won Jong Kim, Chulhong Kim   +5 more
wiley   +1 more source

Offsetting ROS-Mediated Arrest of Endothelial Fenestration Dynamics Permits Long-Term Optical Super-Resolution Imaging Validated by AFM. [PDF]

ACS Appl Mater Interfaces
Kiel A, Luty M, Kralemann-Köhler A, Helweg LP, Schürstedt-Seher J, Kotlinowski J, Pospíšil J, Lekka M, Ly TD, Huser T, Schulte Am Esch J, Hübner W, Szafranska K, Zapotoczny B.   +13 more
europepmc   +1 more source

Isomeric effect on the properties of tetraplatinated porphyrins showing optimized phototoxicity for photodynamic therapy

, 2017
Thiago Teixeira Tasso, Tayana Mazin Tsubone, Maurı́cio S. Baptista, Lia Mallmann Mattiazzi, Thiago V. Acunha, Bernardo A. Iglesias   +5 more
openalex   +1 more source

Regularized Single‐Cell Imaging Enables Generalizable AI Models for Stain‐Free Cell Viability Screening

Small Methods, EarlyView.
Recent advances in AI suggest the potential for stain‐free cell viability screening on brightfield microscopy images. However, no model has been reliably generalized across previously unseen cell types and compounds. Here, we show that “regularized imaging” of single cells in nanowells enables training of generalizable AI models for stain‐free ...
Pan Deng, Deasung Jang, Samuel G. Berryman, Simon P. Duffy, Hongshen Ma   +4 more
wiley   +1 more source

Bioconjugates of Toluidine Blue Derivatives with Human Serum Albumin and Their Complexes with Cucurbit[7]uril as Drug Delivery Vehicles for Photodynamic Therapy. [PDF]

ACS Omega
Mariño-Ocampo N, Robinson-Duggon J, Zúñiga-Núñez D, Guerra Díaz D, Heyne B, Fuentealba D.   +5 more
europepmc   +1 more source

Pirfenidone-induced dose-dependent phototoxicity – a distinct drug reaction

, 2020
Reena Rai, P Arunprasath, Chaitra Venkataswamy   +2 more
openalex   +1 more source

Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

VIEW, EarlyView.
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan, Tao Ye, Yawei Bi, Jiayu Zhang, Wei Wu, Aochi Liu, Li Sun, Jie Lin, Ningli Chai, Manjie Zhang, Jian Ma   +10 more
wiley   +1 more source

The Current State of Research in the Field of Photosensitizers and Photoactivators for Photodynamic/Photothermal Cancer Therapy: A Review. [PDF]

Int J Mol Sci
Yudaev P, Aleksandrova Y, Chugunova E, Neganova M.   +3 more
europepmc   +1 more source

Modifications of Microvascular EC Surface Modulate Phototoxicity of a Porphycene anti-ICAM-1 Immunoconjugate; Therapeutic Implications

, 2013
Elisabet Rosàs, Pablo Santomá, Miquel Duran‐Frigola, Bryan Hernandez, Maria C. Llinàs, Rubén Ruiz‐González, Santi Nonell, David Sánchez‐García, Elazer R. Edelman, Mercedes Balcells   +9 more
openalex   +1 more source

Phototoxic damage to cone photoreceptors can be independent of the visual pigment: the porphyrin hypothesis [PDF]

, 2020
Mélanie Marie, Valérie Forster, Stéphane Fouquet, Pascal Berto, Coralie Barrau, Camille Ehrismann, José‐Alain Sahel, Gilles Tessier, Serge Picaud   +8 more
openalex   +1 more source