Results 81 to 90 of about 34,272 (324)

Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins

Advanced Science, EarlyView.
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan, Chong Zhang, Stanislav Ott, Zhiyi Zhang, Christiane Ruse, Sven Dannhäuser, Robert Jacobi, Nadine Ehmann, Divya Sachidanandan, Georg Nagel, Manfred Heckmann, Robert J. Kittel, Alexander Gottschalk, Adam Claridge‐Chang, Shiqiang Gao   +14 more
wiley   +1 more source

Alpha-ketoglutarate protects Streptomyces coelicolor from visible light-induced phototoxicity

Biochemistry and Biophysics Reports, 2017
It has been known that some Streptomyces species, including the model strain Streptomyces coelicolor, are vulnerable to visible light. Much evidence demonstrated that the phototoxicity induced by visible light is a consequence of the formation of ...
Feng Xu, Jin Wang, Guo-Ping Zhao
doaj   +1 more source

Doxycycline Phototoxicity: A Cautionary Tale for Travelers [PDF]

, 2021
Komal Paradkar, Melanie Wolf, Joy Mosser‐Goldfarb   +2 more
openalex   +1 more source

Like a bolt from the blue : phthalocyanines in biomedical optics [PDF]

, 2011
The purpose of this review is to compile preclinical and clinical results on phthalocyanines (Pcs) as photosensitizers (PS) for Photodynamic Therapy (PDT) and contrast agents for fluorescence imaging.
Ackroyd, Adigbli, Agarwal, Agarwal, Ahmad, Airley, Ali, Ali, Allemann, Allemann, Allemann, Allen, Allison, Allison, Allison, Alonso, Anderson, Apolikhin, Ball, Banfi, Barge, Baron, Baugh, Ben-Hur, Ben-Hur, Betancourt, Bonnett, Boyle, Boyle, Brasseur, Bridges, Brown, Brown, Budzinskaia, Carcenac, Carcenac, Cauchon, Chan, Chan, Cheng, Choi, Claessens, Colussi, Cruse-Sawyer, de Oliveira, Decreau, Derycke, Devlin, Dietze, Dolmans, Duan, Dubuc, Dumoulin, Dutta, Dye, Ethirajan, Ethirajan, Fabris, Fadel, Fattal, Fei, Feofanov, Ferreira, Foley, Fotinos, Fukuda, Fukushima, Gabriel, Gabriel, Gao, Geng, Gijsens, Glassberg, Herlambang, Hogset, Hu, Huang, Huang, Huang, Hubert van den Bergh, Iyer, Jeremy, Jiang, Jori, Jori, Jori, Josefsen, Jux, Karmakova, Karrer, Koval, Kudrevich, Kyriazi, Lagoda, Lang, Lange, Lau, Le, Lee, Likhvantseva, Liu, Liu, Liu, Lo, Longo, Love, MacDonald, Marcus, Master, Mathai, Matsumura, McKeown, McKeown, Medina, Mody, Nawal Sekkat, Nesterova, Nesterova, Norbert Lange, Norum, Norum, Norum, Nyman, Nyokong, Ochsner, Oerlemans, Ometto, O’Hagan, Peng, Peng, Petritsch, Polo, Potter, Prasmickaite, Qualls, Rio, Rosenthal, Roy, Ruebner, Sandeman, Schieweck, Schmidt-Erfurth, Seotsanyana-Mokhosi, Sevick-Muraca, Sharman, Sibrian-Vazquez, Stummer, Stylli, Stylli, Taillefer, Taillefer, Tebello Nyokong, Thomas, Torchilin, Tralau, Trushina, Tuncel, Tyagi, Valduga, van den, van Nostrum, Vrouenraets, Vrouenraets, Whitacre, Whitacre, Winkelman, Wohrle, Xiao, Yegen, Zellweger, Zhao, Zheng   +171 more
core   +4 more sources

An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring

Advanced Science, EarlyView.
Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar, Marc A. Fernandez‐Yague, Adrien Bessaguet, Hosoowi Lee, Nicolas Giuseppone, Andrés J. García, Aránzazu del Campo   +6 more
wiley   +1 more source

Citrus limon (Lemon) Phenomenon—A Review of the Chemistry, Pharmacological Properties, Applications in the Modern Pharmaceutical, Food, and Cosmetics Industries, and Biotechnological Studies

Plants, 2020
This review presents important botanical, chemical and pharmacological characteristics of Citrus limon (lemon)—a species with valuable pharmaceutical, cosmetic and culinary (healthy food) properties.
Marta Klimek-Szczykutowicz, Agnieszka Szopa, Halina Ekiert   +2 more
doaj   +1 more source

Dual Role of Subphthalocyanine Dyes for Optical Imaging and Therapy of Cancer [PDF]

, 2018
This is the peer-reviewed version of the following article: van de Winckel, E., Mascaraque, M., Zamarrón, A., Juarranz de la Fuente, Á., Torres, T., & de la Escosura, A. (2018).
Escosura Navazo, Andrés de la, Juarranz de la Fuente, Ángeles, Mascaraque Checa, Marta, Torres Cebada, Tomás, van de Winckel, Eveline, Zamarrón, Alicia   +5 more
core   +1 more source

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

Advanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang, Honglin Tan, Colleen Russell, Mikolaj Walczak, Dawei Gao, Guanda Qiao, Xiaoxuan Fan, Chengyan Chu, Miroslaw Janowski, Piotr Walczak, Yajie Liang   +10 more
wiley   +1 more source

Porphyrinoid biohybrid materials as an emerging toolbox for biomedical light management [PDF]

, 2018
The development of photoactive and biocompatible nanomaterials is a current major challenge of materials science and nanotechnology, as they will contribute to promoting current and future biomedical applications.
Almeida-Marrero, Verónica, Anaya-Plaza, Eduardo, de la Escosura, Andrés, Torres, Tomás, van de Winckel, Eveline   +4 more
core   +2 more sources

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

Advanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu, Peng Wang, Qing‐Hua Shen, Qi‐Xin Guan, Zhi‐Yuan Li, Ying‐Ying Han, Xin‐Yi Zhang, Qing‐Yuan Hu, Cai‐Ping Tan   +8 more
wiley   +1 more source