Results 81 to 90 of about 32,210 (274)
Characterization of Vemurafenib Phototoxicity in a Mouse Model [PDF]
, 2017 Vemurafenib is a first-in-class, small molecule B-Raf kinase inhibitor for the treatment of patients with unresectable or metastatic melanoma carrying the BRAFV600E mutation, commercially available since 2011.
Bauer, Daniel +3 more
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Refractive Index‐Corrected Light‐Sheet Microscopy for Macro‐View Cardiovascular Imaging
Advanced Science, EarlyView.A refractive index‐corrected light‐sheet fluorescence microscopy system enables macro‐view cardiovascular imaging across organs, adapting to refractive index variations from different optical clearing protocols. By integrating axial sweeping, multi‐view imaging, and a sealed chamber, it extends the field of view, enhances isotropy, and improves safety.
Enbo Zhu +13 more
wiley +1 more source
Photosensitivity : light, sun and pharmacy [PDF]
, 2010 Light has a profound effect on us. We may not be conscious enough as regards the existences of many phototoxic substances and chemicals. A phototoxic substance is a chemical compound which becomes toxic when exposed to light.
Zammit, Mark L.
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Advanced Science, EarlyView.DNA‐Based Genetic and Non‐Genetic Tools for Receptor Engineering. This review highlights recent advances in DNA‐based strategies for receptor engineering, including genetic approaches like domain fusion and site‐directed mutagenesis, as well as non‐genetic methods using functional nucleic acids, DNA nanostructures, and dynamic DNA reactions.
Hexin Nan +4 more
wiley +1 more source
Molecules, 2017 6-Thioguanine, an immunosuppressant and anticancer prodrug, has been shown to induce DNA damage and cell death following exposure to UVA radiation. Its metabolite, 6-thioguanosine, plays a major role in the prodrug’s overall photoreactivity.
Brennan Ashwood +2 more
doaj +1 more source
Characterisation of Two Photosensitizing Compounds from Typhonium Flagelliforme Schott and Their Mode of Action in Inducing Cancer Cell Death [PDF]
, 2002 A bio-assay guided approach was used to isolate photosensitizing compounds from Typhonium flagelliforme Schott, a plant considered by local communities to possess anticancer properties.
Ho, Anthony Siong Hock
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Images in cardiovascular medicine : multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery [PDF]
, 2007 Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial ...
Baker, Andrew H. +7 more
core +1 more source
Advanced Science, EarlyView.Bacterial cell walls (CWs) extracted from Porphyromonas gingivalis are nanofabricated to form the CW vesicles (CWV), which have intrinsic peroxidase‐mimicking and sonodynamic activities due to the presence of µ‐oxo bisheme and meanwhile retain a large amount of lipopolysaccharide.
Meng Yang +9 more
wiley +1 more source
Water‐Soluble Molecular Wires for Membrane Potential Imaging
Angewandte Chemie, EarlyView.Fully water‐soluble fluorescent rosamine‐based amphiphilic molecular wires were developed for imaging membrane potentials. The performance of the probes was evaluated in single cardiomyocytes, murine pituitary gland, and islets of Langerhans.
Mirna El Khatib +9 more
wiley +2 more sources
Light exposure from microscope versus intracameral illumination during cataract surgery
Indian Journal of Ophthalmology, 2019 Purpose: To evaluate light exposure from microscope versus intracameral illuminations to patient's and surgeon's retina during cataract surgery. Methods: Thirty consecutive patients who had cataract surgery using microscope and intracameral illuminations.
Yu Jeong Kim +7 more
doaj +1 more source