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Phthalates: Toxicology and exposure
International Journal of Hygiene and Environmental Health, 2007Phthalates are used as plasticizers in PVC plastics. As the phthalate plasticizers are not chemically bound to PVC, they can leach, migrate or evaporate into indoor air and atmosphere, foodstuff, other materials, etc. Consumer products containing phthalates can result in human exposure through direct contact and use, indirectly through leaching into ...
Ursel, Heudorf +2 more
exaly +3 more sources
Phthalates biodegradation in the environment
Applied Microbiology and Biotechnology, 2008Phthalates are synthesized in massive amounts to produce various plastics and have become widespread in environments following their release as a result of extensive usage and production. This has been of an environmental concern because phthalates are hepatotoxic, teratogenic, and carcinogenic by nature.
Dawei Liang +2 more
exaly +5 more sources
Metabolism of phthalates in humans
Molecular Nutrition and Food Research, 2007AbstractPhthalates are synthetic compounds widely used as plasticisers, solvents and additives in many consumer products. Several animal studies have shown that some phthalates possess endocrine disrupting effects. Some of the effects of phthalates seen in rats are due to testosterone lowering effects on the foetal testis and they are similar to those ...
Hanne Frederiksen, Anna Maria Andersson
exaly +4 more sources
Toxicology Mechanisms and Methods, 2014
Many of the environmental, occupational and industrial chemicals are able to generate reactive oxygen species (ROS) and cause oxidative stress. ROS may lead to genotoxicity, which is suggested to contribute to the pathophysiology of many human diseases, including inflammatory diseases and cancer.
Pınar, Erkekoglu, Belma, Kocer-Gumusel
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Many of the environmental, occupational and industrial chemicals are able to generate reactive oxygen species (ROS) and cause oxidative stress. ROS may lead to genotoxicity, which is suggested to contribute to the pathophysiology of many human diseases, including inflammatory diseases and cancer.
Pınar, Erkekoglu, Belma, Kocer-Gumusel
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Acta Crystallographica Section C Crystal Structure Communications, 2001
The crystals of the new melaminium salt, 2,4,6-triamino-1,3,5-triazin-1-ium hydrogenphthalate, C3H7N6+.C8H5O4-, are built up from single protonated melaminium residues and single dissociated hydrogenphthalate(1-) anions. The protonated melaminium ring is almost planar.
J, Janczak , G J, Perpétuo
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The crystals of the new melaminium salt, 2,4,6-triamino-1,3,5-triazin-1-ium hydrogenphthalate, C3H7N6+.C8H5O4-, are built up from single protonated melaminium residues and single dissociated hydrogenphthalate(1-) anions. The protonated melaminium ring is almost planar.
J, Janczak , G J, Perpétuo
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Biodegradation of phthalates and phthalate esters
Proceedings / Indian Academy of Sciences, 1984Several microorganisms utilising terephthalate and diethylphthalate have been isolated from garden soil. Protocatechuate was one of the intermediates in the degradation of terephthalic acid and diethylphthalate. Accumulation of protocatechuate during the growth of these strains has been described.
T B Karegoudar, B G Pujar
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Regulatory Toxicology and Pharmacology, 2009
Phthalate esters are found in a wide variety of consumer and food packing products. Hence there is widespread exposure of the human population to these chemicals. Some of the phthalate esters are known to be toxic to the developing male reproductive system.
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Phthalate esters are found in a wide variety of consumer and food packing products. Hence there is widespread exposure of the human population to these chemicals. Some of the phthalate esters are known to be toxic to the developing male reproductive system.
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Biological impact of phthalates
Toxicology Letters, 2013Esters of phthalic acid are chemical agents used to improve the plasticity of industrial polymers. Their ubiquitous use in multiple commercial products results in extensive exposure to humans and the environment. This study investigated cytotoxicity, endocrine disruption, effects mediated via AhR, lipid peroxidation and effects on expression of enzymes
Rishikesh, Mankidy +3 more
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Phthalates in the NICU: a survey
Archives of Disease in Childhood - Fetal and Neonatal Edition, 2019Phthalates are chemicals used to enhance the flexibility, solidity and durability of plastics. In neonatal intensive care units (NICU), neonates are exposed to phthalates percutaneously, through drugs, blood transfusions and medical devices (MD) used for ventilation, infusions, nutrition, with daily doses potentially exceeding by far doses considered ...
Myriam Bickle-Graz +2 more
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