Results 71 to 80 of about 65,167 (186)
Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells
Allergy, EarlyView.We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller +16 more
wiley +1 more source
Marine Drugs, 2019 Microalgae of the genus Porphyridium show great potential for large-scale commercial cultivation, as they accumulate large quantities of B-phycoerythrin (B-PE), long chain polyunsaturated fatty acids (LC-PUFAs) and exopolysaccharide (EPS).
Tao Li +5 more
doaj +1 more source
Purification and characterization of phycoerythrin from Rhodosorus marinus
, 1996 Three phycoerythrins ie B-phycoerythrinl (B-PE-1), B-phycoerythrin 2 (B-PE-2) and b-phycoerythrin (b-PE) from Rhodosorus marinus were purified to electrophoresis purity: The molecular weights of the three phycoerythrins and their subunits were determined.
Li Shaorong, Lin Huimin +1 more
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Pre‐Seasonal Treatment With Recombinant Carrier‐Based Birch Vaccine Improves Birch Pollen Allergy
Allergy, EarlyView.We conducted a two stage SCIT trial with GNR‐127 containing a recombinant fusion protein consisting of Bet v 1 and Mal d 1‐derived peptides fused to PreS from HBV. Stage 1 identified two safe maximum tolerated doses (40 μg and 80 μg). In the following Stage 2, five preseasonal injections were well tolerated, induced dose‐dependent allergen‐specific IgG,
Musa R. Khaitov +43 more
wiley +1 more source
A Colorful Pallet of B-Phycoerythrin Proteoforms Exposed by a Multimodal Mass Spectrometry Approach [PDF]
, 2019 Cyanobacteria and red algae represent some of the oldest lifeforms on the planet. During billions of years of evolution, they have fine-tuned the structural details of their light-harvesting antenna, called phycobilisomes, which represents one of the ...
Leney, Aneika C. +7 more
core +2 more sources
Study on Separation of Phycoerythrin by Q-Sepharose Fast Flow
, 2012 This study aimed to establish an efficient process for separation of phycoerythrin by using Q Sepharose Fast Flow resin and verify its feasibility.[Method] Elution gradient,loading volume and flow rate were optimized to determine the optimal separation ...
Gao M(高敏) +5 more
core
Combining TAG‐72CAR with anti‐MUC16CAR improves the potency of ovarian cancer treatment
The FEBS Journal, EarlyView.Tz‐KBBCAR, a combinatorial CAR targeting MUC16 and TAG‐72, enhances the precision of ovarian cancer immunotherapy. By requiring both tumour antigens for full activation, Tz‐KBBCAR was designed to eliminate MUC16+/TAG‐72+ cancer cells, while sparing MUC16+/TAG‐72‐ healthy cells.
Alicia Villatoro +13 more
wiley +1 more source
One-step chromatographic procedure for purification of B-phycoerythrin from Porphyridium cruentum
, 2016 B-phycoerythrin (B-PE) was separated and purified from microalga Porphyridium cruentum using one-step chromatographic method. Phycobiliproteins in P. cruentum was extracted by osmotic shock and initially purified by ultrafiltration.
Tang, ZH (reprint author), Yantai Univ, Coll Life Sci, 30 Qingquan St, Yantai 264005, Peoples R China. zhhtang6@163.com +7 more
core +1 more source
Chronic Excessive Exercise Aggravates Apical Periodontitis in Mice
International Endodontic Journal, EarlyView.ABSTRACT Aim To investigate the effects of overtraining on the development of apical periodontitis (AP) in mice. Methodology Sixty 6‐week‐old male C57BL/6 mice were allocated to six groups: sedentary without AP (SED); sedentary with AP (SED AP); aerobic training without AP (AERO); aerobic training with AP (AERO AP); overtraining without AP (OVER); and ...
Andréia Bosco Boaventura +6 more
wiley +1 more source
Phycoerythrin Production by a Marine Osdilatoria (Cyanophyta)
, 2002 The production of the commercially important pigment phycoerythrin by the marine cyanobacterium $\mathbi{Oscillatoria}$ UMACC 216 was investigated. The cultures from different stages of growth (day 2, 4, 6, 8 and 10) were harvested for the determination ...
Alw, Afnani +2 more
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