Results 121 to 130 of about 465,608 (240)

Origin of subgenomes in the circumboreal, allopolyploid, carnivorous plant Drosera anglica

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise The parentage of the widespread allopolyploid Drosera anglica, a member of the carnivorous sundew genus, remains uncertain despite over 100 years of morphological, cytological, and, more recently, molecular study. Methods Using transcriptomic and genomic data from 12 species of Drosera sect. Drosera, including four D.
Rebekah A. Mohn, Ya Yang
wiley   +1 more source

Characterizing the causes and consequences of calcium oxalate crystal presence in Vitis riparia

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Calcium oxalate biomineralization in plants is phylogenetically widespread and morphologically diverse, but the function of these inorganic crystals is an area of active debate. The variety of environmental conditions that produce the crystals, as well as the inconsistent evidence that they provide antiherbivore defense across plant ...
Carolyn D. K. Graham   +3 more
wiley   +1 more source

Drivers of insect herbivory resistance and tolerance to plant damage in the Brachypodium distachyon species complex

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Insect herbivory is a major biotic factor shaping plant populations and driving the evolution of defensive traits. Polyploidy (whole‐genome duplication) often induces substantial phenotypic and genotypic changes that may affect species interactions, including herbivory.
Antonio J. Manzaneda   +4 more
wiley   +1 more source

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu   +6 more
wiley   +1 more source

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao   +5 more
wiley   +1 more source

Confined B‐Cell Reconstruction and High T‐Cell Clonality Define Clinical Response to Cladribine Treatment

open access: yesAnnals of Neurology, EarlyView.
Cladribine tablets are approved for relapsing multiple sclerosis, mediating their clinical effect by moderately depleting lymphocytes. In a prospective, monocentric study including 22 patients completing 2 annual cycles of cladribine, B‐ and T‐cell receptor repertoires and relapse activity were assessed at baseline and after 24 months. T‐cell clonality
Tilman Schneider‐Hohendorf   +8 more
wiley   +1 more source

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