Results 71 to 80 of about 512,434 (294)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Community‐level phylogenetic diversity does not differ between rare and common lineages across tallgrass prairies in the northern Great Plains

Ecology and Evolution, 2022
Niche differentiation has served as one explanation for species coexistence, and phylogenetic relatedness provides a means to approximate how ecologically similar species are to each other.
Sarah A. Herzog, Maribeth Latvis
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Warming alters elevation distributions of soil bacterial and fungal communities in alpine grasslands

Global Ecology and Conservation, 2022
It is still unknown whether climate warming can change the elevation distribution of soil microbial communities in alpine grasslands. Both species and phylogenetic β-diversity of soil bacterial and fungal communities were investigated at three alpine ...
Fusong Han, Chengqun Yu, Gang Fu
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Global hotspots of plant phylogenetic diversity

New Phytologist, 2023
SummaryRegions harbouring high unique phylogenetic diversity (PD) are priority targets for conservation. Here, we analyse the global distribution of plant PD, which remains poorly understood despite plants being the foundation of most terrestrial habitats and key to human livelihoods.Capitalising on a recently completed, comprehensive global checklist ...
Melanie Tietje, Alexandre Antonelli, Félix Forest, Rafaël Govaerts, Stephen A. Smith, Miao Sun, William J. Baker, Wolf L. Eiserhardt   +7 more
openaire   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Urbanisation and the loss of phylogenetic diversity in birds [PDF]

Ecology Letters, 2017
AbstractDespite the recognised conservation value of phylogenetic diversity, little is known about how it is affected by the urbanisation process. Combining a complete avian phylogeny with surveys along urbanisation gradients from five continents, we show that highly urbanised environments supported on average 450 million fewer years of evolutionary ...
Sol, Daniel, Bartomeus, Ignasi, González-Lagos, César, Pavoine, Sandrine   +3 more
openaire   +7 more sources

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Phylogenetic structure is determined by patch size in rock outcrop vegetation on an inselberg in the northern Amazon region [PDF]

Acta Amazonica, 2018
Although inselbergs from around the world are iconic ecosystems, little is known on the underlying mechanisms of community assembly, especially in their characteristic patchy outcrop vegetation.
Pedro Manuel VILLA, Markus GASTAUER, Sebastião Venâncio MARTINS, Juan Fernando CARRIÓN, Prímula Viana CAMPOS, Alice Cristina RODRIGUES, Gustavo HERINGER, João Augusto Alves MEIRA-NETO   +7 more
doaj   +2 more sources