Results 61 to 70 of about 512,676 (325)

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

open access: yesAdvanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li   +9 more
wiley   +1 more source

The Shape and Dimensionality of Phylogenetic Tree-Space Based on Mitochondrial Genomes [PDF]

open access: yes, 2010
Phylogenetic analyses of large and diverse data sets generally result in large sets of competing phylogenetic trees. Consensus tree methods used to summarize sets of competing trees discard important information regarding the similarity and distribution ...
James C. Wilgenbusch   +2 more
core   +1 more source

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

open access: yesAdvanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch   +4 more
wiley   +1 more source

Phylophenetic properties of metabolic pathway topologies as revealed by global analysis

open access: yesBMC Bioinformatics, 2006
Background As phenotypic features derived from heritable characters, the topologies of metabolic pathways contain both phylogenetic and phenetic components.
Sun Shiwei   +9 more
doaj   +1 more source

Building a Robust, Densely-Sampled Spider Tree of Life for Ecosystem Research

open access: yesDiversity, 2020
Phylogenetic relatedness is a key diversity measure for the analysis and understanding of how species and communities evolve across time and space.
Nuria Macías-Hernández   +11 more
doaj   +1 more source

Measures of clade confidence do not correlate with accuracy of phylogenetic trees. [PDF]

open access: yesPLoS Computational Biology, 2007
Metrics of phylogenetic tree reliability, such as parametric bootstrap percentages or Bayesian posterior probabilities, represent internal measures of the topological reproducibility of a phylogenetic tree, while the recently introduced aLRT (approximate
Barry G Hall, Stephen J Salipante
doaj   +1 more source

Mass Spectrometry Imaging‐Assisted Discovery of Gallotannin Biosynthetic Genes in the Root of Paeonia suffruticosa

open access: yesAdvanced Science, EarlyView.
An integrated approach combining mass spectrometry imaging, transcriptomics, and phylogenetic analysis facilitated the efficient identification of genes involved in gallotannin biosynthesis in Paeonia suffruticosa. As a result, a key UGT and several SCPL acyltransferases responsible for biosynthesizing pentagalloylglucose were successfully identified ...
Yushi Liu   +4 more
wiley   +1 more source

The enigmatic monotypic crab plover Dromas ardeola is closely related to pratincoles and coursers (Aves, Charadriiformes, Glareolidae)

open access: yesGenetics and Molecular Biology, 2010
The phylogenetic placement of the monotypic crab plover Dromas ardeola (Aves, Charadriiformes) remains controversial. Phylogenetic analysis of anatomical and behavioral traits using phenetic and cladistic methods of tree inference have resulted in ...
Sergio L. Pereira, Allan J. Baker
doaj   +1 more source

Gene tree reconciliation: new developments in Bayesian concordance analysis with BUCKy [PDF]

open access: yes, 2010
When phylogenetic trees inferred from different genes are incongruent, several methods are available to reconcile gene trees and extract the shared phylogenetic information from the sequence data. Bayesian Concordance Analysis, implemented in BUCKy, aims
Bret R. Larget   +3 more
core   +1 more source

On Tree-Based Phylogenetic Networks [PDF]

open access: yesJournal of Computational Biology, 2016
A large class of phylogenetic networks can be obtained from trees by the addition of horizontal edges between the tree edges. These networks are called tree based networks. Reticulation-visible networks and child-sibling networks are all tree based. In this work, we present a simply necessary and sufficient condition for tree-based networks and prove ...
openaire   +3 more sources

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