Results 71 to 80 of about 3,378,468 (350)
Geometry of the Space of Phylogenetic Trees
Advances in Applied Mathematics, 2001 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Louis J. Billera +2 more
openaire +3 more sources
Coalescent-based genome analyses resolve the early branches of the euarchontoglires [PDF]
, 2013 Despite numerous large-scale phylogenomic studies, certain parts of the mammalian tree are extraordinarily difficult to resolve. We used the coding regions from 19 completely sequenced genomes to study the relationships within the super-clade ...
Vikas Kumar +10 more
core +1 more source
BiGG Models 2020: multi-strain genome-scale models and expansion across the phylogenetic tree
Nucleic Acids Res., 2019 The BiGG Models knowledge base (http://bigg.ucsd.edu) is a centralized repository for high-quality genome-scale metabolic models. For the past 12 years, the website has allowed users to browse and search metabolic models.
C. J. Norsigian +6 more
semanticscholar +1 more source
Tropical Geometry of Phylogenetic Tree Space: A statistical Perspective [PDF]
Vietnam Journal of Mathematics, 2018 Phylogenetic trees are the fundamental mathematical representation of evolutionary processes in biology. They are also objects of interest in pure mathematics, such as algebraic geometry and combinatorics, due to their discrete geometry.
Anthea Monod +3 more
semanticscholar +1 more source
The Future of Systematics: Tree-Thinking Without the Tree [PDF]
, 2012 Phylogenetic trees are meant to represent the genealogical history of life and apparently derive their justification from the existence of the tree of life and the fact that evolutionary processes are tree-like.
Velasco, Joel D.
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
On Symmetries in Phylogenetic Trees
The Electronic Journal of Combinatorics, 2016 Billey et al. [arXiv:1507.04976] have recently discovered a surprisingly simple formula for the number $a_n(\sigma)$ of leaf-labelled rooted non-embedded binary trees (also known as phylogenetic trees) with $n\geq 1$ leaves, fixed (for the relabelling action) by a given permutation $\sigma\in\frak{S}_n$.
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A Stochastic Model for Phylogenetic Trees [PDF]
Journal of Applied Probability, 2009 We propose the following simple stochastic model for phylogenetic trees. New types are born and die according to a birth and death chain. At each birth we associate a fitness to the new type sampled from a fixed distribution. At each death the type with the smallest fitness is killed. We show that if the birth (i.e.
Liggett, Thomas M., Schinazi, Rinaldo B.
openaire +3 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source