Results 81 to 90 of about 2,045,161 (322)

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

open access: yesAdvanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li   +7 more
wiley   +1 more source

Building a Robust, Densely-Sampled Spider Tree of Life for Ecosystem Research

open access: yesDiversity, 2020
Phylogenetic relatedness is a key diversity measure for the analysis and understanding of how species and communities evolve across time and space.
Nuria Macías-Hernández   +11 more
doaj   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

open access: yesAdvanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha   +13 more
wiley   +1 more source

Evolview v2: an online visualization and management tool for customized and annotated phylogenetic trees

open access: yesNucleic Acids Res., 2016
Evolview is an online visualization and management tool for customized and annotated phylogenetic trees. It allows users to visualize phylogenetic trees in various formats, customize the trees through built-in functions and user-supplied datasets and ...
Zilong He   +5 more
semanticscholar   +1 more source

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

open access: yesAdvanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia   +5 more
wiley   +1 more source

Adaptation to Leaf Traits of Individual Trees in a Forest Appears Rare in Caterpillars

open access: yesEcology and Evolution
High herbivore abundances on trees surrounded by distantly related neighbors (phylogenetic isolation) might in part be due to local adaptation of herbivores to host trees, but this has not been tested.
Freerk Molleman   +4 more
doaj   +1 more source

Bayesian inference of ancestral dates on bacterial phylogenetic trees

open access: yesbioRxiv, 2018
The sequencing and comparative analysis of a collection of bacterial genomes from a single species or lineage of interest can lead to key insights into its evolution, ecology or epidemiology.
X. Didelot   +4 more
semanticscholar   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

open access: yesAdvanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun   +5 more
wiley   +1 more source

PhyloJS: Bridging phylogenetics and web development with a JavaScript utility library

open access: yesEcology and Evolution
There is an increasing number of libraries devoted to parsing, manipulating and visualising phylogenetic trees in JavaScript. Many of these libraries bundle tree manipulation with visualisation, but have limited ability to manipulate trees and lack ...
Leo A. Featherstone, Wytamma Wirth
doaj   +1 more source

Lassoing and corraling rooted phylogenetic trees

open access: yes, 2013
The construction of a dendogram on a set of individuals is a key component of a genomewide association study. However even with modern sequencing technologies the distances on the individuals required for the construction of such a structure may not ...
A. Dress   +17 more
core   +1 more source

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