Results 61 to 70 of about 149,860 (254)

A scalable method for identifying frequent subtrees in sets of large phylogenetic trees

BMC Bioinformatics, 2012
Background We consider the problem of finding the maximum frequent agreement subtrees (MFASTs) in a collection of phylogenetic trees. Existing methods for this problem often do not scale beyond datasets with around 100 taxa.
Ramu Avinash, Kahveci Tamer, Burleigh J Gordon   +2 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Visualizations for taxonomic and phylogenetic trees [PDF]

Bioinformatics, 2004
Abstract Motivation: Despite substantial efforts to develop and populate the back-ends of biological databases, front-ends to these systems often rely on taxonomic expertise. This research applies techniques from human–computer interaction research to the biodiversity domain.
Cynthia Sims Parr, Bongshin Lee, Dana Campbell, Benjamin B. Bederson   +3 more
openaire   +2 more sources

Coordinated Architectural and Chemical Reinforcement in the Crushing Mandible of a Soldier Termite

Advanced Functional Materials, EarlyView.
The crushing mandible of a soldier termite withstands substantial biting loads despite lacking mineral. Its cuticle is partitioned: convex teeth pair hardness and zinc enrichment with aligned chitin fibers for contact durability, while stiffer concave regions between teeth carry bending loads.
Andrew Tran Nguyen, Patryk Wąsik, Juan Fernando Cucuyame Morales, Marie Kate Palau, Adrian Francisco Duran Ornelas, Phani Saketh Dasika, Jin Hee Kim, Radhika Laxminarayana, Eric Hintsala, Greta Chang, Junzhi Liao, Lizhi Sun, Nathan Lord, Atsushi Arakaki, Paul Bardunias, Pablo Zavattieri, David Kisailus   +16 more
wiley   +1 more source

Incongruencies in Vaccinia Virus Phylogenetic Trees

Computation, 2014
Over the years, as more complete poxvirus genomes have been sequenced, phylogenetic studies of these viruses have become more prevalent. In general, the results show similar relationships between the poxvirus species; however, some inconsistencies are ...
Chad Smithson, Samantha Kampman, Benjamin M. Hetman, Chris Upton   +3 more
doaj   +1 more source

Material Before Morphology: Substrate‐Dependent Mechanical Tuning of Radular Teeth

Advanced Materials Interfaces, EarlyView.
Substrate‐dependent material tuning in Clausilia radular teeth. Closely related taxa retain a conserved gross tooth morphology, but differ in elemental composition and mechanical properties according to feeding substrate. Rock‐associated taxa show increased Ca–Si enrichment and higher stiffness and hardness, especially in the central radular region ...
Ida Lilienthal, Bernhard Hausdorf, Stanislav N. Gorb, Wencke Krings   +3 more
wiley   +1 more source

Building a Robust, Densely-Sampled Spider Tree of Life for Ecosystem Research

Diversity, 2020
Phylogenetic relatedness is a key diversity measure for the analysis and understanding of how species and communities evolve across time and space.
Nuria Macías-Hernández, Marc Domènech, Pedro Cardoso, Brent C. Emerson, Paulo Alexandre Vieira Borges, Jesús Lozano-Fernandez, Octávio S. Paulo, Ana Vieira, Alba Enguídanos, François Rigal, Isabel R. Amorim, Miquel A. Arnedo   +11 more
doaj   +1 more source

A six nuclear gene phylogeny of Citrus (Rutaceae) taking into account hybridization and lineage sorting. [PDF]

PLoS ONE, 2013
BACKGROUND: Genus Citrus (Rutaceae) comprises many important cultivated species that generally hybridize easily. Phylogenetic study of a group showing extensive hybridization is challenging.
Chandrika Ramadugu, Bernard E Pfeil, Manjunath L Keremane, Richard F Lee, Ivan J Maureira-Butler, Mikeal L Roose   +5 more
doaj   +1 more source