Results 41 to 50 of about 149,599 (256)
On Symmetries in Phylogenetic Trees
The Electronic Journal of Combinatorics, 2016 Billey et al. [arXiv:1507.04976] have recently discovered a surprisingly simple formula for the number $a_n(\sigma)$ of leaf-labelled rooted non-embedded binary trees (also known as phylogenetic trees) with $n\geq 1$ leaves, fixed (for the relabelling action) by a given permutation $\sigma\in\frak{S}_n$.
openaire +3 more sources
Analysis on Algorithms for Constructing Phylogenetic Trees From Distances
IEEE Access, 2019 Neighbour-joining algorithm (NJ for short) is an used widely algorithm for constructing phylogenetic trees from distances because of its high accuracy. For NJ costs a lot of time to construct phylogenetic trees for the large input data, it does not often
Juan Wang
doaj +1 more source
Generating normal networks via leaf insertion and nearest neighbor interchange
BMC Bioinformatics, 2019 Background Galled trees are studied as a recombination model in theoretical population genetics. This class of phylogenetic networks has been generalized to tree-child networks and other network classes by relaxing a structural condition imposed on ...
Louxin Zhang
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Cherry picking in forests: A new characterization for the unrooted hybrid number of two phylogenetic trees [PDF]
Discrete Mathematics & Theoretical Computer SciencePhylogenetic networks are a special type of graph which generalize phylogenetic trees and that are used to model non-treelike evolutionary processes such as recombination and hybridization. In this paper, we consider {\em unrooted} phylogenetic networks,
Katharina T. Huber +2 more
doaj +1 more source
TreeSwift: A massively scalable Python tree package
SoftwareX, 2020 Phylogenetic trees are essential to evolutionary biology, and numerous methods exist that attempt to extract phylogenetic information applicable to a wide range of disciplines, such as epidemiology and metagenomics.
N. Moshiri
doaj +1 more source
A strict upper bound for the partition distance and the cluster distance of phylogenetic trees for each fixed pair of topological trees. [PDF]
PLoS ONE, 2018 For each given pair of (rooted or unrooted) topological trees with the same number of leaves a strict upper bound is shown for the tree partition distance (also called symmetric difference metric and Robinson-Foulds distance)-in case of unrooted trees ...
Martin Middendorf, Nicolas Wieseke
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source