Results 61 to 70 of about 30,396 (259)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Is it time to abandon the flow cytometry in estimations of genome size when the K-mer analysis is available? The case of Engelhardia species

open access: yesGenomics Communications
Genome size represents a fundamental genomic trait with profound implications across evolutionary biology, ecology, and genomics. Flow cytometry (FCM) has served as the gold standard for estimating genome size for decades, while the advent of next ...
Min Li   +9 more
doaj   +1 more source

DNA barcodes reveal population-dependent cryptic diversity and various cases of sympatry of Korean leptonetid spiders (Araneae: Leptonetidae)

open access: yesScientific Reports, 2022
Leptonetidae are tiny, rarely encountered spiders that mainly inhabit moist environments, such as caves, leaf litter, and rock piles. Because they are microhabitat specialists, most leptonetid species have short-range endemism, and rarely occur in ...
Jong-Hwa Oh, Sora Kim, Seunghwan Lee
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

A Format for Phylogenetic Placements

open access: yesPLoS ONE, 2012
We have developed a unified format for phylogenetic placements, that is, mappings of environmental sequence data (e.g. short reads) into a phylogenetic tree. We are motivated to do so by the growing number of tools for computing and post-processing phylogenetic placements, and the lack of an established standard for storing them.
Matsen, Frederick A.   +3 more
openaire   +6 more sources

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Phylogenetic Web Profiler [PDF]

open access: yesBioinformatics, 2003
Abstract Summary: Phylogenetic Web Profiler (PWP) is a web-based service designed to perform phylogenetic profiling of proteins against genomes. The current version offers a selection of 63 completed genomes and available plasmids as annotated in the PEDANT genome database.
Philip Wong   +3 more
openaire   +2 more sources

Survey of molecular phylogenetics

open access: yesPlant, Soil and Environment, 2007
Rapidly increasing amount of biological data necessarily requires techniques that would enable to extract the information hidden in the data. Methods of molecular phylogenetics are commonly used tools as well as objects of continuous research within many
M. Talianová
doaj   +1 more source

Quartets enable statistically consistent estimation of cell lineage trees under an unbiased error and missingness model

open access: yesAlgorithms for Molecular Biology, 2023
Cancer progression and treatment can be informed by reconstructing its evolutionary history from tumor cells. Although many methods exist to estimate evolutionary trees (called phylogenies) from molecular sequences, traditional approaches assume the ...
Yunheng Han, Erin K. Molloy
doaj   +1 more source

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