Results 41 to 50 of about 30,747 (258)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Positive selection and relaxed purifying selection contribute to rapid evolution of sex-biased genes in green seaweed Ulva

BMC Ecology and Evolution
Background The evolution of differences in gamete size and number between sexes is a cornerstone of sexual selection theories. The green macroalga Ulva, with incipient anisogamy and parthenogenetic gametes, provides a unique system to investigate ...
Xiaojie Liu, Jonas Blomme, Kenny A. Bogaert, Sofie D’hondt, Emma Coulembier Vandelannoote, Thomas Wichard, Olivier De Clerck   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The first mitochondrial genome of Calophyllum soulattri Burm.f.

Scientific Reports
Calophyllum soulattri Burm.f. is traditionally used to treat skin infections and reduce rheumatic pain, yet genetic and genomic studies are still limited. Here, we present the first complete mitochondrial genome of C. soulattri.
Charles Anthon E. Cadorna, Dexter G. Pahayo, Jessica D. Rey   +2 more
doaj   +1 more source

Strong intraspecific trait variation in a tropical dominant tree species along an elevational gradient

Plant Diversity, 2020
Functional trait variation of plant species includes both inter- and intraspecific variation; however, trait-based plant ecology generally considers only interspecific variation while ignoring intraspecific variation.
Wumei Xu, Kyle W. Tomlinson, Jie Li
doaj   +1 more source

The noctuid moth Xylomoia graminea (Lepidoptera: Noctuidae) new to the Romanian fauna [PDF]

Travaux du Muséum National d’Histoire Naturelle “Grigore Antipa”, 2020
In this paper, new data concerning the occurrence and distribution of Xylomoia graminea (Graeser, 1889) in Romania are given. Pictures of specimen and male genitalia are provided.
Constantin Corduneanu, Cătălin-Dumitrel Balan, Cristina Vasiliţa, Ovidiu‑Alin Popovici   +3 more
doaj   +3 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The phylogenetic regression

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1989
Abstract A new statistical method called the phylogenetic regression is proposed that applies multiple regression techniques to cross-species data. It allows continuous and categorical variables to be tested for and controlled for. The new method is valid despite the problem that phylogenetically close species tend to be similar, and ...
openaire   +2 more sources

Phylogenetics and the origin of species [PDF]

Proceedings of the National Academy of Sciences, 1997
A recent criticism that the biological species concept (BSC) unduly neglects phylogeny is examined under a novel modification of coalescent theory that considers multiple, sex-defined genealogical pathways through sexual organismal pedigrees. A competing phylogenetic species concept (PSC) also is evaluated from this vantage.
Avise, John C, Wollenberg, Kurt
openaire   +4 more sources