Toward a genomic understanding of the tree of life. [PDF]
Mol Biol EvolSpang A, Pisani D.
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, Volume 20, Issue 10, Page 2490-2509, October 2026.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Mitogenome structure and phylogenomics of the order Thoreales (Nemaliophycidae, Rhodophyta). [PDF]
J PhycolPaiano MO +6 more
europepmc +1 more source
Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila
Advanced Science, Volume 13, Issue 56, 9 October 2026.While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li +7 more
wiley +1 more source
Reply to Szöllősi and Williams: The observation threshold mitigates the bias of transient genes on ancestral reconstruction. [PDF]
Proc Natl Acad Sci U S AGagnon V, Csűrös M.
europepmc +1 more source
Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia
Advanced Science, Volume 13, Issue 57, 14 October 2026.Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li +8 more
wiley +1 more source
Correction to: The Meaning and Measure of Concordance Factors in Phylogenomics. [PDF]
Mol Biol Evoleuropepmc +1 more source
Conserved intracellular virulence architecture and focal genomic diversification in sub-Saharan African <i>Brucella melitensis</i>. [PDF]
Microbiol SpectrBahati SY +5 more
europepmc +1 more source
Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota
Advanced Science, Volume 13, Issue 60, 28 October 2026.Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal +25 more
wiley +1 more source
Loss, persistence and reversal of phenotypic traits
Biological Reviews, Volume 101, Issue 5, Page 2119-2133, October 2026.ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni +4 more
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