Results 111 to 120 of about 550,864 (311)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

The new genus of stick insect Lobofemora from Vietnam, with the description of three new species (Phasmida: Phasmatidae: Clitumnini)

open access: yesEuropean Journal of Taxonomy, 2015
The new genus Lobofemora gen. nov. is described from Vietnam to accommodate three new species: L. bachmaensis sp. nov. (Bach Ma National Park, central Vietnam), L. bidoupensis sp. nov. (Bidoup-Nui Ba National Park, central Vietnam) and L.
Joachim Bresseel, Jérôme Constant
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Phylogeny and species differentiation of four wild almond species of subgen. <i>Amygdalus</i> in China

open access: diamond, 2021
Chuncheng Wang   +6 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Potential of rare actinomycetes in the production of metabolites against multiple oxidant agents

open access: yesPharmaceutical Biology, 2018
Context: Actinobacteria are a precious source of novel bioactive metabolites with potential pharmaceutical applications. Objectives: Representatives of 11 genera of rare Actinobacteria were selected for the evaluation of antioxidant activity.
Fatemeh Mohammadipanah, Mana Momenilandi
doaj   +1 more source

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