Results 111 to 120 of about 548,823 (344)
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Multilocus perspectives on the monophyly and phylogeny of the order Charadriiformes (Aves) [PDF]
Matthew G. Fain, Peter Houde
openalex +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Potential of rare actinomycetes in the production of metabolites against multiple oxidant agents
Context: Actinobacteria are a precious source of novel bioactive metabolites with potential pharmaceutical applications. Objectives: Representatives of 11 genera of rare Actinobacteria were selected for the evaluation of antioxidant activity.
Fatemeh Mohammadipanah, Mana Momenilandi
doaj +1 more source
Combined molecular and morphological phylogeny of Eulophidae (Hymenoptera: Chalcidoidea), with focus on the subfamily Entedoninae [PDF]
Roger A. Burks +3 more
openalex +1 more source
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
The MAPKKK and MAPKK gene families in banana: identification, phylogeny and expression during development, ripening and abiotic stress [PDF]
Lianzhe Wang +10 more
openalex +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
The problem of phylogeny orientation and bioenergetic progress: new model of life evolution [PDF]
Yu. A. Naletov, Y.A Naletov
openalex +1 more source

