Results 61 to 70 of about 538,243 (358)

Studies of nonhuman primates: key sources of data on zoonoses and microbiota

New Microbes and New Infections, 2018
The genetic and morphologic similarities between primates and humans means that much information obtained from primates may be applied to humans, and vice versa.
B. Davoust, A. Levasseur, O. Mediannikov
doaj   +1 more source

Phylogeny of Gammaproteobacteria [PDF]

Journal of Bacteriology, 2010
ABSTRACT The phylogeny of the large bacterial class Gammaproteobacteria has been difficult to resolve. Here we apply a telescoping multiprotein approach to the problem for 104 diverse gammaproteobacterial genomes, based on a set of 356 protein families for the whole class and even larger sets for each of ...
Joshua M. Shallom, Kelly P. Williams, Bruno W. S. Sobral, Joseph J. Gillespie, Eric K. Nordberg, Allan W. Dickerman, Eric E. Snyder   +6 more
openaire   +3 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Deep‐sea caridean shrimps collected from the South China Sea with emphasizing their phylogenetic relationships

Ecology and Evolution
Despite the high biological and ecological diversity of the South China Sea, limited research has been conducted on the deep‐sea species diversity of caridean shrimps.
Zhibin Gan, Xuefeng Fang, Xinzheng Li
doaj   +1 more source

Massilimicrobiota timonensis gen. nov., sp. nov., a new bacterium isolated from the human gut microbiota

New Microbes and New Infections, 2019
Massilimicrobiota timonensis gen. nov., sp. nov. strain Marseille-P2264 is a new species from Firmicutes phylum isolated from the human gut. Its genome was 2,849,574 bp-long with a 31.8% G+C content.
M.L. Tall, S. Ndongo, I.I. Ngom, J. Delerce, S. Khelaifia, D. Raoult, P.-E. Fournier, A. Levasseur   +7 more
doaj   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

First Genomic Survey of Pleurocryptella shinkai Provides Preliminary Insights into Genome Characteristics and Evolution of a Deep-Sea Parasitic Isopod

Diversity
Genomic adaptations of parasitic crustaceans in deep-sea extreme environments are poorly understood. This study presents the first genome survey of Pleurocryptella shinkai, a bopyrid isopod parasitizing deep-sea squat lobsters, using Illumina sequencing.
Aiyang Wang, Min Hui, Zhongli Sha
doaj   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

DNA taxonomy reveals high species diversity among the stygobiont genus Metastenasellus (Crustacea, Isopoda) in African groundwater [PDF]

Subterranean Biology
This study aimed to explore the species diversity within the isopod genus Metastenasellus in Benin and Cameroon. Compared to other parts of the world, the described diversity of stygobiotic crustaceans in Africa is low due to a dearth of studies and ...
Moïssou Lagnika, Raoul Polycarpe Tuekam Kayo, Gontran Sonet, Jean-François Flot, Patrick Martin   +4 more
doaj   +3 more sources

The Phylogeny of Rationality [PDF]

Cognitive Science, 1993
A rational agent has beliefs reflecting the state of its environment, and likes or dislikes Its situation. When it finds the world not entirely to Its liking, it tries to change that. We can, accordingly, evaluate a system of cognition in terms of its probable success in bringing about situations that are to the agent's liking.
openaire   +2 more sources