Results 71 to 80 of about 478,847 (346)

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

open access: yesFEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra   +7 more
wiley   +1 more source

Inferring Transcript Phylogenies [PDF]

open access: yes2011 IEEE International Conference on Bioinformatics and Biomedicine, 2011
Alternative splicing, an unknown mechanism 20 years ago, is now recognized as a major mechanism for proteome and transcriptome diversity, particularly in mammals–some researchers conjecture that up to 90% of human genes are alternatively spliced. Despite much research on exon and intron evolution, little is known about the evolution of transcripts.
Christinat, Yann, Moret, Bernard
openaire   +6 more sources

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

Giant Sticks from Vietnam and China, with three new taxa including the second longest insect known to date (Phasmatodea, Phasmatidae, Clitumninae, Pharnaciini)

open access: yesEuropean Journal of Taxonomy, 2014
Two new species and one subspecies of Pharnaciini, belonging to two different genera, are described from Vietnam: one species and subspecies of Phryganistria Stål, 1875 and one species of Phobaeticus Brunner von Wattenwyl, 1907.
Joachim Bresseel, Jérôme Constant
doaj   +1 more source

Persistent Phylogeny: A Galled-Tree and Integer Linear Programming Approach [PDF]

open access: yesarXiv, 2015
The Persistent-Phylogeny Model is an extension of the widely studied Perfect-Phylogeny Model, encompassing a broader range of evolutionary phenomena. Biological and algorithmic questions concerning persistent phylogeny have been intensely investigated in recent years.
arxiv  

The Complexity of Rooted Phylogeny Problems

open access: yes, 2010
Several computational problems in phylogenetic reconstruction can be formulated as restrictions of the following general problem: given a formula in conjunctive normal form where the literals are rooted triples, is there a rooted binary tree that ...
Bodirsky, Manuel, Mueller, Jens K
core   +2 more sources

The Phylogeny of Rationality [PDF]

open access: yesCognitive Science, 1993
A rational agent has beliefs reflecting the state of its environment, and likes or dislikes Its situation. When it finds the world not entirely to Its liking, it tries to change that. We can, accordingly, evaluate a system of cognition in terms of its probable success in bringing about situations that are to the agent's liking.
openaire   +2 more sources

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

A Simple Characterization of the Minimal Obstruction Sets for Three-State Perfect Phylogenies [PDF]

open access: yesarXiv, 2011
Lam, Gusfield, and Sridhar (2009) showed that a set of three-state characters has a perfect phylogeny if and only if every subset of three characters has a perfect phylogeny. They also gave a complete characterization of the sets of three three-state characters that do not have a perfect phylogeny.
arxiv  

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

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