Results 71 to 80 of about 548,823 (344)
Inferring clonal evolution of tumors from single nucleotide somatic mutations [PDF]
, 2013 High-throughput sequencing allows the detection and quantification of frequencies of somatic single nucleotide variants (SNV) in heterogeneous tumor cell populations.
Deshwar, Amit G. +4 more
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
DiversityDuring two expeditions to the seamounts in the Yap-Caroline area of the Western Pacific, a new genus, Phoxirostus gen. nov., in the family Laphystiopsidae Stebbing, 1899, is erected for two new species, P. longicarpus sp. nov.
Yanrong Wang, Zhongli Sha, Xianqiu Ren
doaj +1 more source
European Journal of Taxonomy, 2018 Two new species of the family Selachinematidae Cobb, 1915 from an intertidal sandy flat in the East China Sea are described. Both species are distinct rapacious nematodes, preying on other nematodes. Gammanema magnum sp. nov. is characterized by its leaf-
Benze Shi, Kuidong Xu
doaj +1 more source
Massilistercora timonensis gen. nov., sp. nov., a new bacterium isolated from the human microbiota
New Microbes and New Infections, 2020 Massilistercora timonensis gen. nov., sp. nov. strain Marseille-P3756T is a new species of the phylum Firmicutes; it was isolated from the human gut microbiota and has a genome of 2 769 591 bp (51.2% G + C). The closest species based on 16S rRNA sequence
M.L. Tall +7 more
doaj +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Morphological and DNA sequence data uncover a new millipede species in the Thyropygus opinatus subgroup and assign T. peninsularis to this subgroup (Diplopoda: Spirostreptida: Harpagophoridae) [PDF]
PeerJThe millipede genus Thyropygus Pocock, 1894 is one of the most diverse genera within the family Harpagophoridae in Southeast Asia. The Thyropygus opinatus subgroup, belonging to the T.
Piyatida Pimvichai +4 more
doaj +2 more sources
Unique Perfect Phylogeny Characterizations via Uniquely Representable Chordal Graphs
, 2013 The perfect phylogeny problem is a classic problem in computational biology, where we seek an unrooted phylogeny that is compatible with a set of qualitative characters.
Gysel, Rob
core
Inferring evolutionary histories of pathway regulation from transcriptional profiling data [PDF]
, 2013 One of the outstanding challenges in comparative genomics is to interpret the evolutionary importance of regulatory variation between species. Rigorous molecular evolution-based methods to infer evidence for natural selection from expression data are at ...
Brem, Rachel B. +3 more
core +4 more sources
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source