<i>Rumex</i> Species: Phytochemistry, Pharmacology and Nutritional Potential for Food and Health Applications. [PDF]
Rumex dentatus, R. vesicarius, and Emex spinosa are traditionally used for managing gastrointestinal, respiratory, hepatic, and inflammatory disorders. In addition to their ethnomedicinal value, some species are consumed as wild edibles. Pharmacological studies support their antimicrobial, antioxidant, hepatoprotective, cytotoxic, and antidiabetic ...
Mohamed Gohar M +10 more
europepmc +2 more sources
The anti-breast cancer property of physcion via oxidative stress-mediated mitochondrial apoptosis and immune response [PDF]
Context Physcion (Phy) exerts several pharmacological effects including anti-inflammatory, antioxidant, and antitumor properties. Objective This study investigates the cytotoxicity and its underlying mechanisms of Phy on breast cancer.
Luping Zhang +6 more
openalex +2 more sources
MICROWAVE-ASSISTED RAPID SYNTHESIS OF PHYSCIONS DERIVATIVES UNDER SOLVENT FREE CONDITION
The 1- and 8-O-alkylated physcions derivatives are easily synthesized in good yields upon exposure to microwave irradiation under solvent free conditions and reaction times are considerable ...
I MANOJLOVI +3 more
openalex +3 more sources
Retraction Note: Physcion, a naturally occurring anthraquinone derivative, induces apoptosis and autophagy in human nasopharyngeal carcinoma. [PDF]
Pang MJ +5 more
europepmc +3 more sources
Torosachrysone and physcion gentiobiosides from the seeds of Cassia torosa.
Susumu Kitanaka, Michio Takido
openalex +3 more sources
Physcion alleviates chronic alcoholic hepatic inflammation and pyroptosis through SIRT1-AMPK activation [PDF]
BACKGROUND AND PURPOSE Alcohol-associated liver disease (ALD) caused by chronic alcohol consumption range from simple steatosis to alcoholic hepatitis, fibrosis, and cirrhosis. Physcion is an anthraquinone compound of Rheum palmatum L, a Chinese herbal medicine with possible hepatoprotective properties.
Ting Bai +7 more
openalex +2 more sources
Estrogenic activities of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside and physcion in MCF-7 cells
Polygonum multiflorum (PM) is a perennial herbal medicine that inhibits osteopenia of osteoporosis caused by estrogen deficiency and shows estrogen-like activity.
Su-Jin Kim, Yun-Ho Hwang, Sung-Tae Yee
doaj +1 more source
Pharmacodynamics of Five Anthraquinones (Aloe-emodin, Emodin, Rhein, Chysophanol, and Physcion) and Reciprocal Pharmacokinetic Interaction in Rats with Cerebral Ischemia [PDF]
(1) Background: Rhubarb anthraquinones—a class of components with neuroprotective function—can be used to alleviate cerebral ischemia reperfusion injury.
Rongrong Li +7 more
openalex +2 more sources
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+FoxP3+ regulatory T cells activation [PDF]
Rationale: Loss of histone macroH2A1 induces appearance of cancer stem cells (CSCs)-like cells in hepatocellular carcinoma (HCC). How CSCs interact with the tumor microenvironment and the adaptive immune system is unclear. Methods: We screened aggressive
Drovakova A. +11 more
core +1 more source
Emex spinosa (L.) Campd.: A Review on Ethnomedicinal, Phytochemical, Pharmacological, and Toxicological Profile. [PDF]
Graphical abstract illustrating the pharmacological potential of E. spinosa. ABSTRACT Emex spinosa (L.) Campd. (E. spinosa) is a plant species belonging to the Polygonaceae family. It is native to the Middle East, North Africa, and Europe and is most commonly seen on the coastlines of Mediterranean countries.
Amtaghri S +9 more
europepmc +2 more sources

