Results 91 to 100 of about 5,913,205 (362)

Effectiveness of Intervention Strategies to Increase Adolescents’ Physical Activity and Reduce Sedentary Time in Secondary School Settings, Including Factors Related to Implementation: A Systematic Review and Meta-Analysis

open access: yesSports Medicine - Open
Background Globally, just one in five adolescents meet physical activity guidelines and three-quarters of the school day is spent sitting. It is unclear which types of school-based interventions strategies increase physical activity and reduce sedentary ...
Ana María Contardo Ayala   +9 more
doaj   +1 more source

Effects of beetroot juice supplementation on intermittent high-intensity exercise efforts

open access: yesJournal of the International Society of Sports Nutrition, 2018
Beetroot juice contains high levels of inorganic nitrate (NO3 −) and its intake has proved effective at increasing blood nitric oxide (NO) concentrations.
Raúl Domínguez   +8 more
doaj   +1 more source

Physical activity promotion [PDF]

open access: yesBritish Journal of General Practice, 2010
Davies and Garbutt wrote an important and commendable editorial on exercise prescription;1 however, there are some fundamental issues raised requiring clarification and further consideration. First, when measured objectively, a staggering 95% of the adult population (UK and US) do not meet the minimum recommended levels of physical activity to confer ...
openaire   +3 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Physical activity and mental well-being [PDF]

open access: yes, 2013
There is increasing research into the relationship between physical activity and mental health. Evidence shows that for adults at least 30 minutes of moderate intensity physical activity on most days of the week can improve mood and decrease ...
Gauci, Charmaine
core  

The Benefits of Physical Activity on Depression [PDF]

open access: yes, 2020
Physical exercise can be an effective counter-measure against depression. Activity need not be strenuous and it may reduce the risk for depression, even among those with a family history or genetic disposition for depression. And depression in itself may
Ansello, Edward F.
core   +1 more source

The Feasibility of a Novel School Peer-Led Mentoring Model to Improve the Physical Activity Levels and Sedentary Time of Adolescent Girls: The Girls Peer Activity (G-PACT) Project

open access: yesChildren, 2018
Regular physical activity (PA) is associated with numerous physical and psychological health benefits. Adolescents, specifically girls, are at risk of physical inactivity.
Michael B. Owen   +7 more
doaj   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

open access: yesMolecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin   +10 more
wiley   +1 more source

Acceptability of Social Media Incentives to Increase Physical Activity [PDF]

open access: yes, 2019
Background: Contingency management can be effective in promoting physical activity, but the change frequently does not sustain after the intervention is withdrawn. A feasible and sustainable physical activity intervention is needed. Social media may meet
DeFulio, Anthony, Devoto, Amanda
core   +1 more source

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